Epigenome-Wide Association Study for 28-Day Survival of Acute Respiratory Distress Syndrome

Details

• Personal Author:
  Christiani, David C. ; Guo Y ; Shen S ; Su L ; Zhang R ; Zhu Z
• Description:
  To our knowledge, this is the first genome-wide epigenetic study among ARDS patients. While the sample size is limited, the discovered methylation sites showed putative biological importance, which highlights the feasibility of future large studies on DNA methylation in ARDS. In addition, the methylation risk score may ultimately be clinically useful for ARDS prognostic indication. [Description provided by NIOSH]
• Subjects:
  Biomarkers Genetics Lung Diseases Mortality Occupational Health Respiratory System Respiratory Tract Diseases Safety
• Keywords:
  Genes Genetic Factors Lung Disease Mortality Rates Respiratory Diseases
• ISSN:
  0342-4642
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Massachusetts ; OSHA Region 1
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  44
• Issue:
  7
• NIOSHTIC Number:
  nn:20056654
• Citation:
  Intensive Care Med 2018 Jul; 44(7):1182-1184
• Contact Point Address:
  David C. Christiani, Pulmonary and Critical Care Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
• Email:
  dchris@hsph.harvard.edu
• Federal Fiscal Year:
  2018
• Performing Organization:
  Harvard School of Public Health
• Peer Reviewed:
  False
• Start Date:
  20050701
• Source Full Name:
  Intensive Care Medicine
• End Date:
  20280630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:8dfc6c0e344b5b43dea8a54d2b409af4a02228ea2629fd816af3a761cce2d7cb21d7bb24ea447082f1049ec5489e6f3fcda5fe2d73118fa509867fc440e8e0e5
• Download URL:
  https://stacks.cdc.gov/view/cdc/214212/cdc_214212_DS1.pdf
• File Type:
  [PDF - 646.52 KB ]