Workplace and Other Overuse Injuries
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2008/01/31
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Personal Author:
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Description:All of the findings in animal and human experiments on local and systemic increases in metabolites and cytokines lend credence to the hypothesis that localized tissue-level responses to exercise loading lead to the resolution of any injury through normal repair processes as long as the initiating stimulus is removed. The findings also show that low-intensity exercise can cause injuries to muscle through mechanical disruption, hypoxia, or by-products of metabolism. Once injury occurs, an immune response is initiated. In cases in which the injury stimulus persists, this immune response is amplified and perpetuated until its mediators are distributed throughout the circulatory system. Such circulatory distribution may cause tissue effects in distant anatomical sites and may have psychoneuroirnmunological effects on mood and behavior. Furthermore, if task intensity is high enough, the normal tissue repair process may be interrupted to the extent that permanent tissue changes occur, thereby rendering tissues more susceptible to future injury even at previously innocuous levels of task intensity. Obviously, this vicious cycle of injury, inflammation, scarring, and behavioral dysfunction should be avoided. [Description provided by NIOSH]
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ISBN:9780736058674
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Pages in Document:147-162
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NIOSHTIC Number:nn:20056427
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Citation:Skeletal Muscle Damage and Repair. Tiidus PM ed. Champaign, IL: Human Kinetics, 2008 Jan; :147-162
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Federal Fiscal Year:2008
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Performing Organization:Temple University
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Peer Reviewed:False
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Start Date:20000601
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Source Full Name:Workplace and other overuse injuries
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End Date:20120731
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Main Document Checksum:urn:sha-512:25850378b3076bf9d0da4c81785b2126137d2ba372bf8107911988ca535dcc5f4eebbfaadc208032a76ff899ba9576787e8e54381fd6555ee7cfe71582126745
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