Blood Cadmium and Moderate-to-Severe Glomerular Dysfunction in Korean Adults: Analysis of KNHANES 2005–2008 Data

Details

• Personal Author:
  Baker, Dean B. ; Choi B ; Kim H-R ; Myong J-P
• Description:
  Purpose: The objective of this study was to evaluate the association between blood cadmium (Cd) and moderate-to-severe glomerular dysfunction in a Korean population using a representative sample. Methods: A cross-sectional study was used to evaluate the association between blood Cd and glomerular dysfunction. Based on the Korean National Health and Nutrition Examination Survey (2005-2008), individual blood Cd was measured in 2,992 adults, aged between 20 and 65. Results: After adjusting for survey years, age, sociodemographic factors, and health behaviors, the odds ratio for moderate-to-severe glomerular dysfunction (<60 mL/min per 1.73 m2) was 1.97 (95% CI: 1.28-3.07) when comparing the highest with the lowest blood Cd quartile in Korean women. However, in Korean men, there was no association between blood Cd and moderate-to-severe glomerular dysfunction. Conclusions: These findings support the consideration of Cd as a risk factor for glomerular dysfunction in the female population. Furthermore, environmental heavy metal monitoring and an institutional strategy should be implemented to reduce Cd exposure in the general population. Description provided by NIOSH
• Subjects:
  • Cadmium
  • Environmental Exposure
  • Men
  • Metals, Heavy
  • Occupational Health
  • Safety
  • Women
• Keywords:
  • Cross sectional studies
  • Cadmium
  • Kidney disorders
  • Women
  • Men
  • Heavy metals
  • Exposure levels
  • Author Keywords: Cadmium
  • Glomerular filtration rate
  • Kidney diseases
  More +
• ISSN:
  0340-0131
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  85
• Issue:
  8
• NIOSHTIC Number:
  nn:20056040
• Citation:
  Int Arch Occup Environ Health 2012 Nov; 85(8):885-893
• Contact Point Address:
  H. W. Yim, Department of Preventive Medicine and Clinical Research Center for Depression, College of Medicine, The Catholic University of Korea, 505 BanPo-dong Seocho-gu, Seoul 137-701, Republic of Korea
• Email:
  cyclor@catholic.ac.kr
• CAS Registry Number:
  • Cadmium (CAS RN 7440-43-9)
• Federal Fiscal Year:
  2013
• Performing Organization:
  University of California Los Angeles
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  International Archives of Occupational and Environmental Health
• End Date:
  20270630
• Download URL:
  https://stacks.cdc.gov/view/cdc/213737/cdc_213737_DS1.pdf
• File Type:
  [PDF - 397.38 KB]
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:8ac9ada2a3698a5b2b87bd17bb5d89d625243fce1778925925ad66d7a559fd018e9af8c3b32a8f1f96bd3f1e4cd4e5cd159f276e1c6062240aa2b09f140a0977