Occupational Pesticide Exposures and Risk of Depression in Central California

Details

• Personal Author:
  Lee P-C ; Liew Z ; Narayan S ; Paul K ; Ritz B
• Description:
  Background: Depression is the most common mental disorder worldwide. Pesticides are neurotoxins but human data investigating the link between workplace pesticide exposures and depression are sparse. Methods: We used data from 736 older residents of an agriculturally intensive region of Central California to investigate whether active use and by-stander occupational exposures to pesticides are associated with depression. Participants were older adults enrolled as controls in a study of Parkinson's disease (PD) between 2001-2011. We developed a comprehensive job-exposure-matrix (JEM) based on reported work history information and calculated cumulative exposure scores for pesticides. Information on doctor diagnosis of depression was collected in interviews. To address the time-dependency of exposure and outcome, participants were matched according to the age at first depression occurrence, and we examined only exposures 10 or 20 years prior to this age (categorized as high (>= median), low (
• Subjects:
  Insecticides Mental Disorders Mental Health Nervous System Occupational Exposure Occupational Health Safety
• Keywords:
  Chronic Exposure JEM Job Exposure Matrix Mental Disorders Mental Health Pesticides And Agricultural Chemicals
• Publisher:
  International Society for Environmental Epidemiology
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Abstract or Summary
• Place as Subject:
  California ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• NIOSHTIC Number:
  nn:20055966
• Citation:
  28th Annual Conference of the International Society for Environmental Epidemiology (ISEE 2016), September 1-4, 2016, Rome, Italy. Herndon, VA: International Society for Environmental Epidemiology, 2016 Sep; :O-185
• Federal Fiscal Year:
  2016
• Performing Organization:
  University of California Los Angeles
• Peer Reviewed:
  False
• Start Date:
  20050701
• Source Full Name:
  28th Annual Conference of the International Society for Environmental Epidemiology (ISEE 2016), September 1-4, 2016, Rome, Italy
• End Date:
  20270630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:1a44f68697df73a8644169ca19790d9a607ed6f0f912de45ef7bf2116fd46535e174883a9087fd9429cf08b8d104fb642eb1addf13770a8936e3dbb6bd93c22e
• Download URL:
  https://stacks.cdc.gov/view/cdc/213710/cdc_213710_DS1.pdf
• File Type:
  [PDF - 446.39 KB ]