Bone, Blood and Semen Lead in Men with Environmental and Moderate Occupational Exposure

Details

• Personal Author:
  Amarasiriwardena C ; Aro A ; Echavarria M ; Farias P ; Hernandez L ; Hernandez-Avila M ; Hu H ; Villanueva C
• Description:
  Lead (Pb) in blood, bone, and semen was measured in 162 to 186 environmentally exposed men from Mexico City, aged 19 - 48. Semen Pb was measured by inductively coupled plasma mass spectrometry, blood Pb by atomic absorption spectrometry and bone Pb by K X-ray fluorescence. Mean Pb levels in blood, semen, tibia (cortical) and patella (trabecular) bone were 12 ug/dl, 2.7 ug/l, 13 ug/g, and 20 ug/g, respectively. Semen Pb was determined by blood Pb and patella Pb. Determinants of higher tibia Pb were age, living near industry in which Pb is used, and a high occupational Pb exposure index. Higher patella Pb was predicted by age, higher traffic density near home, a high index of occupational exposure to Pb and a greater number of cigarettes smoked per day in the year prior to the study. Blood and bone Pb results are consistent with findings in other populations. Semen results provide new information on the semen-bone Pb relationship. Bone, especially trabecular one, proved to be a significant endogenous lead source for blood and semen burdens in reproductive aged men. [Description provided by NIOSH]
• Subjects:
  Blood Demography Environmental Exposure Lead Men Occupational Health Risk Assessment Risk Factors Safety Smokers Tobacco Products

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• Keywords:
  Author Keywords: Bone Lead Blood Lead Bone Disorders Cigarette Smoking Demographic Characteristics Environmental Exposure Environmental Lead Exposure Levels Humans K X-ray Fluorescence Mass Spectrometry Risk Factors Semen Lead Smoking

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• ISSN:
  0960-3123
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Massachusetts ; OSHA Region 1
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  21-31
• Volume:
  15
• Issue:
  1
• NIOSHTIC Number:
  nn:20055614
• Citation:
  Int J Environ Health Res 2005 Feb; 15(1):21-31
• Contact Point Address:
  Paulina Farias, Instituto Nacional de Salud Publica, Av. Universidad 655, Col. Sta. Ma. Ahuacatitlan, C.P. 62508, Cuernavaca, Morelos, Mexico
• Email:
  pfarias@correo.insp.mx
• CAS Registry Number:
  Lead (CAS RN 7439-92-1)
• Federal Fiscal Year:
  2005
• Performing Organization:
  Harvard School of Public Health
• Peer Reviewed:
  True
• Start Date:
  20030731
• Source Full Name:
  International Journal of Environmental Health Research
• End Date:
  20050630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:84718e968fcb86ea7d9f3f4df6ec87c909201dbe992e65a3c7162714aaeb96c4c6f96f23be3a70007377a32d3925bbc762c2a967b0d596dbbcc180f624d53d6b
• Download URL:
  https://stacks.cdc.gov/view/cdc/213425/cdc_213425_DS1.pdf
• File Type:
  [PDF - 247.83 KB ]