Menstrual Cycle Changes as Women Approach the Final Menses: What Matters?

Details

• Personal Author:
  Harlow SD
• Description:
  The STRAW+10 bleeding criterion for onset of the early menopausal transition is increased variability (persistent, 7-days or more difference in length of consecutive cycles) and for onset of the late menopausal transition is occurrence of amenorrhea of 60 days or more. Twelve percent to 25% of women experience minimal or no change in their menstrual cycle length before their final menstrual period (FMP). Women with earlier onset of the menopausal transition have longer transitions. When the transition is not sudden, it may last from approximately 4 to 10 years, with longer duration associated with earlier age at onset. Excessive flow and prolonged menstrual bleeding is a hallmark of the menopausal transition. Most women experience repeated bleeding episodes lasting 10 or more days, whereas one-third have heavy menstrual bleeding lasting 3 or more days, with blood loss frequently exceeding 80 mL. Anovulation is common in the menopausal transition, but hormonally normal, ovulatory cycles occur up until the FMP. [Description provided by NIOSH]
• Subjects:
  Age Factors Aging Occupational Health Safety Women
• Keywords:
  Abnormal Uterine Bleeding Age Factors Author Keywords: Menstruation Hormone Activity Menopausal Transition Menopause Menstrual Disorders
• ISSN:
  0889-8545
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Michigan ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  45
• Issue:
  4
• NIOSHTIC Number:
  nn:20055581
• Citation:
  Obstet Gynecol Clin North Am 2018 Dec; 45(4):599-611
• Contact Point Address:
  Siobán D. Harlow PhD, Department of Epidemiology, School of Public Health of the University of Michigan, 1415 Washington Heights, Ann Arbor, MI 48109-2029, USA
• Email:
  harlow@umich.edu
• Federal Fiscal Year:
  2019
• Performing Organization:
  University of Michigan, Ann Arbor
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Obstetrics and Gynecology Clinics of North America
• End Date:
  20280630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:115056311e7ec9b4a6a7b99a7fd32d1d533ec6c508524d359f45a6c075887c48f72b622265b652ef4ec30520e9211361472c537e92869813f308d4e27ccdcc1d
• Download URL:
  https://stacks.cdc.gov/view/cdc/213402/cdc_213402_DS1.pdf
• File Type:
  [PDF - 142.60 KB ]