Details:

Alternative Title:
Am J Trop Med Hyg
Publisher's site:
http://dx.doi.org/10.4269/ajtmh.13-0208
Personal Author:
Jackson, Brendan R.; Talkington, Deborah F.; Pruckler, James M.; Fouché, M. D. Bernadette; Lafosse, Elsie; ... More +
Jackson, Brendan R.; Talkington, Deborah F.; Pruckler, James M.; Fouché, M. D. Bernadette; Lafosse, Elsie; Nygren, Benjamin; Gómez, Gerardo A.; Dahourou, Georges A.; Archer, W. Roodly; Payne, Amanda B.; Hooper, W. Craig; Tappero, Jordan W.; Derado, Gordana; Magloire, Roc; Gerner-Smidt, Peter; Freeman, Nicole; Boncy, Jacques; Mintz, Eric D.; Less -
Corporate Authors:
Cholera Serosurvey Working Group;
Description:
To assess the spectrum of illness from toxigenic Vibrio cholerae O1 and risk factors for severe cholera in Haiti, we conducted a cross-sectional survey in a rural commune with more than 21,000 residents. During March 22-April 6, 2011, we interviewed 2,622 residents ≥ 2 years of age and tested serum specimens from 2,527 (96%) participants for vibriocidal and antibodies against cholera toxin; 18% of participants reported a cholera diagnosis, 39% had vibriocidal titers ≥ 320, and 64% had vibriocidal titers ≥ 80, suggesting widespread infection. Among seropositive participants (vibriocidal titers ≥ 320), 74.5% reported no diarrhea and 9.0% had severe cholera (reported receiving intravenous fluids and overnight hospitalization). This high burden of severe cholera is likely explained by the lack of pre-existing immunity in this population, although the virulence of the atypical El Tor strain causing the epidemic and other factors might also play a role.
Subject:
[+]
Adolescent
Adult
Aged
Aged, 80 And Over
Child
Child, Preschool
Cholera
Female
Humans
Infant
Male
Middle Aged
Odds Ratio
Risk Factors
Seroepidemiologic Studies
Young Adult

Source:
Am J Trop Med Hyg. 2013; 89(4):654-664.;
Series:
AJTMH and PAHO : Commemorating the 3rd Anniversary of the Cholera Outbreak in Haiti : Invited Papers;
Document Type:
Journal Article;
Place as Subject:
Haiti;
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:25543cb54624ddd96606e28c0215420f14a688f934c090cb7a4369348359c851
File Type:

Supporting Files

• 	license.txt	txt
  	tropmed-89-654-g001.gif	gif
  	tropmed-89-654-g001.jpg	jpeg
  	tropmed-89-654-g002.gif	gif
  	tropmed-89-654-g002.jpg	jpeg
  	tropmed-89-654-g003.gif	gif
  	tropmed-89-654-g003.jpg	jpeg
  	tropmed-89-654.nxml	txt

More +