Seroepidemiologic Survey of Epidemic Cholera in Haiti to Assess Spectrum of Illness and Risk Factors for Severe Disease

Jackson, Brendan R.; Talkington, Deborah F.; Pruckler, James M.; Fouché, M. D. Bernadette; Lafosse, Elsie; Nygren, Benjamin; Gómez, Gerardo A.; Dahourou, Georges A.; Archer, W. Roodly; Payne, Amanda B.; Hooper, W. Craig; Tappero, Jordan W.; Derado, Gordana; Magloire, Roc; Gerner-Smidt, Peter; Freeman, Nicole; Boncy, Jacques; Mintz, Eric D.

doi:10.4269/ajtmh.13-0208

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Seroepidemiologic Survey of Epidemic Cholera in Haiti to Assess Spectrum of Illness and Risk Factors for Severe Disease

Published Date:

Oct 2013

Publisher's site:

http://dx.doi.org/10.4269/ajtmh.13-0208 New Site Icon

Source:

Am J Trop Med Hyg. 2013; 89(4):654-664.

[PDF-825.80 KB]

Details:

Alternative Title:

Am J Trop Med Hyg

Personal Author:

Jackson, Brendan R. ; Talkington, Deborah F. ; Pruckler, James M. ; Fouché, M. D. Bernadette ; Lafosse, Elsie ; ... More ▼

Corporate Authors:

Cholera Serosurvey Working Group

Description:

To assess the spectrum of illness from toxigenic Vibrio cholerae O1 and risk factors for severe cholera in Haiti, we conducted a cross-sectional survey in a rural commune with more than 21,000 residents. During March 22-April 6, 2011, we interviewed 2,622 residents ≥ 2 years of age and tested serum specimens from 2,527 (96%) participants for vibriocidal and antibodies against cholera toxin; 18% of participants reported a cholera diagnosis, 39% had vibriocidal titers ≥ 320, and 64% had vibriocidal titers ≥ 80, suggesting widespread infection. Among seropositive participants (vibriocidal titers ≥ 320), 74.5% reported no diarrhea and 9.0% had severe cholera (reported receiving intravenous fluids and overnight hospitalization). This high burden of severe cholera is likely explained by the lack of pre-existing immunity in this population, although the virulence of the atypical El Tor strain causing the epidemic and other factors might also play a role.

Subject:

[+]

Document Type:

Journal Article

Place as Subject:

Haiti

Collection(s):

CDC Public Access

Main Document Checksum:

[+]

Supporting Files:

	license.txt	text/plain
	tropmed-89-654-g001.gif	image/gif
	tropmed-89-654-g001.jpg	image/jpeg
	tropmed-89-654-g002.gif	image/gif
	tropmed-89-654-g002.jpg	image/jpeg
	tropmed-89-654-g003.gif	image/gif
	tropmed-89-654-g003.jpg	image/jpeg
	tropmed-89-654.nxml	text/plain

No Related Documents.

You May Also Like:

Cholera Elimination in Hispaniola

Personal Author:

Etienne, Carissa F.; Tappero, Jordan W.; Marston, Barbara J.; Frieden, Thomas R.; Kenyon, Thomas A.; Andrus, Jon K.;

Published Date:

Oct 2013

Source:

Am J Trop Med Hyg. 2013; 89(4):615-616.

File Type:

[PDF - 425.10 KB]
Identifying the Most Sensitive and Specific Sign and Symptom Combinations for Cholera: Results from an Analysis of Laboratory-Based Surveillance Data from Haiti, 2012–2013

Personal Author:

Lucien, Mentor Ali Ber; Schaad, Nicolas; Steenland, Maria W.; Mintz, Eric D.; Emmanuel, Rossignol; Freeman, Nicole; Boncy, Jacques; Adrien, Paul; Joseph, Gerard A.; Katz, Mark A.;

Published Date:

Mar 02 2015

Source:

Am J Trop Med Hyg. 2015; 92(4):758-764.

Description:

Since October 2010, over 700,000 cholera cases have been reported in Haiti. We used data from laboratory-based surveillance for diarrhea in Haiti to evaluate the sensitivity, specificity, and positive (PPV) and negative predictive values (NPV) of the...

File Type:

[PDF - 634.72 KB]
Training on management of cholera - short course : November, 2010, Departments, Haiti

Corporate Authors:

Centers for Disease Control and Prevention (U.S.)

Published Date:

12/20/10

Description:

As part of CDC’s response to a request from the Haitian Ministry of Public Health and Population (MSPP) for assistance in addressing the recent cholera outbreak, CDC developed interim training materials and other resources to meet this urgent need....

File Type:

[PDF - 1.58 MB]
60th annual EIS Conference; Epidemic Intelligence Service, April 11-15, 2011, Atlanta Marriott Marquis

Corporate Authors:

Centers for Disease Control and Prevention (U.S.), Epidemic Intelligence Service.

Conference Authors:

Epidemic Intelligence Service Conference (60th : 2011 : Atlanta, GA)

Published Date:

4/19/2011

Description:

Publication date from document properties.

File Type:

[PDF - 13.12 MB]
Cholera in the United States

Personal Author:

Wong, Karen K.

Corporate Authors:

United States. Advisory Committee on Immunization Practices.. National Center for Emerging and Zoonotic Infectious Diseases (U.S.). Division of Foodborne, Waterborne, and Environmental Diseases..

Conference Authors:

United States. Advisory Committee on Immunization Practices. Meeting (2015 October 21 : Atlanta, GA)

Published Date:

October 21, 2015

Description:

Slides from a presentation at the Advisory Committee on Immunization Practices meeting October 21, 2015, Atlanta, GA.slides-2015-10/cholera-02-wong.pdf

File Type:

[PDF - 511.30 KB]