Details:

Alternative Title:
Am J Trop Med Hyg
Publisher's site:
http://dx.doi.org/10.4269/ajtmh.13-0208
Personal Author:
Jackson, Brendan R. ; Talkington, Deborah F. ; Pruckler, James M. ; Fouché, M. D. Bernadette ; Lafosse, Elsie ; ... More +
Jackson, Brendan R. ; Talkington, Deborah F. ; Pruckler, James M. ; Fouché, M. D. Bernadette ; Lafosse, Elsie ; Nygren, Benjamin ; Gómez, Gerardo A. ; Dahourou, Georges A. ; Archer, W. Roodly ; Payne, Amanda B. ; Hooper, W. Craig ; Tappero, Jordan W. ; Derado, Gordana ; Magloire, Roc ; Gerner-Smidt, Peter ; Freeman, Nicole ; Boncy, Jacques ; Mintz, Eric D. Less -
Corporate Authors:
Cholera Serosurvey Working Group
Description:
To assess the spectrum of illness from toxigenic Vibrio cholerae O1 and risk factors for severe cholera in Haiti, we conducted a cross-sectional survey in a rural commune with more than 21,000 residents. During March 22-April 6, 2011, we interviewed 2,622 residents ≥ 2 years of age and tested serum specimens from 2,527 (96%) participants for vibriocidal and antibodies against cholera toxin; 18% of participants reported a cholera diagnosis, 39% had vibriocidal titers ≥ 320, and 64% had vibriocidal titers ≥ 80, suggesting widespread infection. Among seropositive participants (vibriocidal titers ≥ 320), 74.5% reported no diarrhea and 9.0% had severe cholera (reported receiving intravenous fluids and overnight hospitalization). This high burden of severe cholera is likely explained by the lack of pre-existing immunity in this population, although the virulence of the atypical El Tor strain causing the epidemic and other factors might also play a role.
Subject:
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Adolescent
Adult
Aged
Aged, 80 And Over
Child
Child, Preschool
Cholera
Female
Humans
Infant
Male
Middle Aged
Odds Ratio
Risk Factors
Seroepidemiologic Studies
Young Adult

Source:
Am J Trop Med Hyg. 2013; 89(4):654-664.
Series:
AJTMH and PAHO : Commemorating the 3rd Anniversary of the Cholera Outbreak in Haiti : Invited Papers
Document Type:
Journal Article
Place as Subject:
Haiti
Collection(s):
CDC Public Access
Main Document Checksum:
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urn:sha256:25543cb54624ddd96606e28c0215420f14a688f934c090cb7a4369348359c851
File Type:

Supporting Files

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