Sleep Deprivation and Metabolism

Details

• Personal Author:
  Hanlon EC ; Knutson KL
• Description:
  Rates of overweight and obesity have been progressively increasing along with associated disorders such as type II diabetes and cardiovascular disease. Concurrently, average sleep times have gradually decreased. The present chapter discusses evidence from both epidemiologic and laboratory studies suggesting that sleep deficiency may contribute to the increased prevalence of overweight and obesity, along with type II diabetes and cardiovascular disease. The most likely mechanisms linking insufficient sleep and overweight/obesity lie within the hypothalamic nuclei involved in modulating feeding and waking behaviors and involve dysregulation of peripheral factors that modulate neural activity in these nuclei. Moreover, the findings provide evidence that sleep deficiency does indeed impair glucose metabolism and alters the cross-talk between periphery and brain, favoring excessive food intake. A better understanding of the adverse effects of sleep deficiency on metabolism and the central nervous system control of hunger and appetite may have important implications for public health. [Description provided by NIOSH]
• Subjects:
  Blood Cardiovascular Diseases Cardiovascular System Energy Metabolism Hematologic Diseases Occupational Health Safety Sleep Sleep Initiation And Maintenance Disorders
• Keywords:
  Author Keywords: Obstructive Sleep Apnea Blood Sugar Disorders Cardiovascular Disease Heart Disease Hormone Activity Lateral Hypothalamus Metabolic Effects Neural Networks Obesity Short Sleep Duration Sleep Apnea Sleep Deprivation Sleep Duration Sleep Loss Weight Factors

  More +
• ISBN:
  9781461490869
• Publisher:
  Springer Science+Business Media
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Book
• Place as Subject:
  Illinois ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  111-129
• NIOSHTIC Number:
  nn:20052762
• Citation:
  Sleep deprivation and disease: effects on the body, brain and behavior. Bianchi MT ed. New York: Springer Science+Business Media, 2014 Jan; :111-129
• Contact Point Address:
  Erin C. Hanlon, Section of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Sleep, Metabolism, and Health Center, University of Chicago, Chicago, USA
• Email:
  ehanlon@medicine.bsd.uchicago.edu
• Editor(s):
  Bianchi MT
• Federal Fiscal Year:
  2014
• Performing Organization:
  University of Chicago
• Peer Reviewed:
  True
• Start Date:
  20090901
• Source Full Name:
  Sleep deprivation and disease: effects on the body, brain and behavior
• End Date:
  20150831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:8d87c308bc83f72c22f9ab96b45370b1218bc1a6a4914254bf45d7083884f355efe0a3941299e31c97fca684b70689ca0b4ea9da472b3facbd781c13d43f643e
• Download URL:
  https://stacks.cdc.gov/view/cdc/212238/cdc_212238_DS1.pdf
• File Type:
  [PDF - 209.79 KB ]