Cardiac Contractility & Oxygen Consumption in Work-Related Heat Syncope

Details

• Personal Author:
  Wilson TE
• Description:
  The conclusions of this project are as follows: The isoproterenol-induced % increase in LVDP was preserved until 40 degrees C, indicating that hearts were unable to generate the same force at this temperature compared to cooler temperatures or to time controls. Temperature did not alter Frank-Starling relations compared to time matched controls. These data indicate that extreme temperatures alter adrenergically mediated force production of the heart, which could lead to compromised stroke volume in certain conditions. Moreover, factors other than just temperature must be altering previous in vivo observations of systolic function increases and cerebral blood flow decreases in mild heat stress. [Description provided by NIOSH]
• Subjects:
  Animals Cardiovascular Diseases Cardiovascular System Heat Stress Disorders Hot Temperature Occupational Health Safety Temperature
• Keywords:
  Cardiac Function Cardiovascular Disease Heat Exhaustion Heat Exposure Heat Stress Myocardial Disorders Temperature Effects
• Publisher:
  University of Cincinnati
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Proceedings
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-20
• NIOSHTIC Number:
  nn:20052628
• Citation:
  12th Annual Pilot Research Project Symposium, University of Cincinnati Education and Research Center, October 13-14, 2011, Cincinnati, Ohio. Cincinnati, OH: University of Cincinnati, 2011 Oct; :1-20
• CAS Registry Number:
  Isoproterenol (CAS RN 7683-59-2)
• Federal Fiscal Year:
  2012
• Performing Organization:
  University of Cincinnati
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  12th Annual Pilot Research Project Symposium, University of Cincinnati Education and Research Center, October 13-14, 2011, Cincinnati, Ohio
• End Date:
  20260630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:516d5e22a1287287d86caba42d35e12e0a2b83cf091cc39e04c5b5d2cad57d788b6109cdf504533e8bc9a3abcb1e7e3a0929366c6f4c3cfab49826f8bdd88b49
• Download URL:
  https://stacks.cdc.gov/view/cdc/212130/cdc_212130_DS1.pdf
• File Type:
  [PDF - 3.67 MB ]