Details:

Alternative Title:
PLoS One
Personal Author:
Stevenson, Jennifer C. ; Stresman, Gillian H. ; Gitonga, Caroline W. ; Gillig, Jonathan ; Owaga, Chrispin ; ... More +
Stevenson, Jennifer C. ; Stresman, Gillian H. ; Gitonga, Caroline W. ; Gillig, Jonathan ; Owaga, Chrispin ; Marube, Elizabeth ; Odongo, Wycliffe ; Okoth, Albert ; China, Pauline ; Oriango, Robin ; Brooker, Simon J. ; Bousema, Teun ; Drakeley, Chris ; Cox, Jonathan ; Less -
Description:
Background School surveys provide an operational approach to assess malaria transmission through parasite prevalence. There is limited evidence on the comparability of prevalence estimates obtained from school and community surveys carried out at the same locality. Methods Concurrent school and community cross-sectional surveys were conducted in 46 school/community clusters in the western Kenyan highlands and households of school children were geolocated. Malaria was assessed by rapid diagnostic test (RDT) and combined seroprevalence of antibodies to bloodstage Plasmodium falciparum antigens. Results RDT prevalence in school and community populations was 25.7% (95% CI: 24.4-26.8) and 15.5% (95% CI: 14.4-16.7), respectively. Seroprevalence in the school and community populations was 51.9% (95% CI: 50.5-53.3) and 51.5% (95% CI: 49.5-52.9), respectively. RDT prevalence in schools could differentiate between low (<7%, 95% CI: 0-19%) and high (>39%, 95% CI: 25-49%) transmission areas in the community and, after a simple adjustment, were concordant with the community estimates. Conclusions Estimates of malaria prevalence from school surveys were consistently higher than those from community surveys and were strongly correlated. School-based estimates can be used as a reliable indicator of malaria transmission intensity in the wider community and may provide a basis for identifying priority areas for malaria control.
Subject:
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Research Article

Source:
PLoS One. 2013 ; 8(10).;
Document Type:
Journal Article ;
Collection(s):
CDC Public Access
Main Document Checksum:
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urn:sha256:ff4ef00d00c8401b7c6e5a89d5eb3a2c63cd2c0ffd98a77924ed6058f41fecc4
File Type:

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