Low Cost, Simple Three Dimensional Electrochemical Paper-Based Analytical Device for Determination of P-Nitrophenol

Details

• Personal Author:
  Henry CS ; Kubota LT ; Santhiago M
• Description:
  We report here the fabrication and electrochemical characterization of a three-dimensional paper-based analytical device made from pencil (hard and soft) and paper as a low-cost, simple, easy-to-use device for p-nitrophenol analysis. The three-dimensional device integrates filtration and was fabricated from conventional printing paper patterned with a wax printer. A quick response code (QR) was added to the device to enable the user to rapidly assess p-nitrophenol information. The counter electrode was drawn on the paper while the working electrode consisted of a short section of graphite obtained from a pencil (30 × 0.3 mm). p-Nitrophenol was selected as the target analyte and basic parameters such as solution pH, buffer concentration, and pulse amplitude were optimized. Under optimized conditions (0.1 M acetate buffer, pH 4.0), a detection limit of 1.1 uM was obtained. The devices showed high sensitivity and a linear range for p-nitrophenol, 10 to 200 uM. The devices were employed to determine p-nitrophenol in water samples and the results showed recoveries ranging from 91.8 to 108.2%. [Description provided by NIOSH]
• Subjects:
  Occupational Health Safety
• Keywords:
  Analytical Instruments Author Keywords: Paper-based Analytical Devices Electrochemical Analysis Electrochemical Detection Graphite Nitrophenols P-nitrophenol Pencil Point-of-need
• ISSN:
  0013-4686
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Colorado ; OSHA Region 8
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  130
• NIOSHTIC Number:
  nn:20052122
• Citation:
  Electrochim Acta 2014 Jun; 130:771-777
• Contact Point Address:
  Lauro T. Kubota, National Institute of Science and Technology in Bioanalytics, Institute of Chemistry-UNICAMP, P.O.Box 6154, Campinas, Brazil
• Email:
  kubota@iqm.unicamp.br
• CAS Registry Number:
  4-Nitrophenol (CAS RN 100-02-7) ; Graphite (CAS RN 7782-42-5)
• Federal Fiscal Year:
  2014
• Performing Organization:
  Colorado State University - Fort Collins
• Peer Reviewed:
  True
• Start Date:
  20110701
• Source Full Name:
  Electrochimica Acta
• End Date:
  20140630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7b9bc38bf280536eebf50ca819028b9576f0556ebde8456a61608a7047b02d4fc5cbb38d3314abd88e5f875348c25d5c6d3b8f190e09653754e3029299f1da0e
• Download URL:
  https://stacks.cdc.gov/view/cdc/211712/cdc_211712_DS1.pdf
• File Type:
  [PDF - 1.70 MB ]