Subclinical Markers of Cardiovascular Disease Among Police Officers: A Longitudinal Assessment of the Cortisol Awakening Response and Flow Mediated Artery Dilation

Details

• Personal Author:
  Andrew, Michael E. ; Charles LE ; Fekedulegn D ; Gu JK ; Miller DB ; Violanti JM
• Description:
  Objective: To examine the association of the cortisol awakening response (CAR) with change in brachial artery flow-mediated dilation (FMD%) in police officers over a seven-year period. Methods: Baseline CAR was obtained from four saliva samples taken fifteen minutes apart immediately after awakening. Analysis of covariance was used to compare the change in FMD% (FMD%Follow-up-FMD%Baseline) across tertiles of area under the cortisol curve with respect to increase (AUCI). Regression analysis was use to assess trend. Results: Officers (n=172; 81% men) had a mean +/- SD age of 41 +/- 7.6 years. Men in the lowest AUCI tertile (i.e., atypical waking cortisol pattern) had a significantly larger seven-year mean decline in FMD% (mean +/- SE: -2.56 +/- 0.64) compared to men in the highest tertile (-0.89 +/- 0.69) (p=0.0087). Conclusion: An awakening cortisol AUCI predicted worsening of FMD% approximately seven years later among male officers. [Description provided by NIOSH]
• Subjects:
  Adrenal Cortex Hormones Blood Cardiovascular Diseases Cardiovascular System Endocrine System Law Enforcement Occupational Health Safety Stress, Psychological
• Keywords:
  Author Keywords: Police Stress Awakening Cortisol BCOPS Blood Pressure Blood Vessels Brachial Reactivity Cardiovascular Disease Corticoids Flow-mediated Dilation Hormone Activity Hormones Job Stress Law Enforcement Workers Longitudinal Study Police Officers Salivary Glands

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• ISSN:
  1076-2752
• Document Type:
  Text
• Funding:
  Grant ; Contract
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2 ; OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  60
• Issue:
  9
• NIOSHTIC Number:
  nn:20051687
• Citation:
  J Occup Environ Med 2018 Sep; 60(9):853-859
• Contact Point Address:
  John M. Violanti, PhD, Department of Epidemiology and Environmental Health, School of Public Health and Health Professions, 270 Farber Hall, University at Buffalo, The State University of New York, Buffalo, New York, USA
• Email:
  violanti@buffalo.edu
• Federal Fiscal Year:
  2018
• NORA Priority Area:
  Public Safety
• Performing Organization:
  State University of New York at Buffalo
• Peer Reviewed:
  True
• Start Date:
  20100901
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• End Date:
  20150831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:9c5df14fe1febac33a1a0a6782d907fa3328f96db71443e75ba5f987b77f60bf985223d81f5c078b8f3cbd771a3622ba6c1ded480b05c6974265cf0e0d4d10df
• Download URL:
  https://stacks.cdc.gov/view/cdc/211507/cdc_211507_DS1.pdf
• File Type:
  [PDF - 266.67 KB ]