Differentiating Gold Nanorod Samples Using Particle Size and Shape Distributions from Transmission Electron Microscope Images

Details

• Personal Author:
  Buhr E ; Burchett WW ; Grulke EA ; Ji Y ; Lambert J ; Schwegler-Berry D ; Stefaniak, Aleksandr B. ; Stromberg AJ ; Woong Song N ; Wu X ; Yamamoto K
• Description:
  Size and shape distributions of gold nanorod samples are critical to their physico-chemical properties, especially their longitudinal surface plasmon resonance. This interlaboratory comparison study developed methods for measuring and evaluating size and shape distributions for gold nanorod samples using transmission electron microscopy (TEM) images. The objective was to determine whether two different samples, which had different performance attributes in their application, were different with respect to their size and/or shape descriptor distributions. Touching particles in the captured images were identified using a ruggedness shape descriptor. Nanorods could be distinguished from nanocubes using an elongational shape descriptor. A non-parametric statistical test showed that cumulative distributions of an elongational shape descriptor, that is, the aspect ratio, were statistically different between the two samples for all laboratories. While the scale parameters of size and shape distributions were similar for both samples, the width parameters of size and shape distributions were statistically different. This protocol fulfills an important need for a standardized approach to measure gold nanorod size and shape distributions for applications in which quantitative measurements and comparisons are important. Furthermore, the validated protocol workflow can be automated, thus providing consistent and rapid measurements of nanorod size and shape distributions for researchers, regulatory agencies, and industry. [Description provided by NIOSH]
• Subjects:
  Chemistry Laboratories Occupational Health Particulate Matter Safety
• Keywords:
  Author Keywords: Gold Nanorod Chemical Properties Electron Microscopy Gold Nanorods Particle Size Physical Properties Samplers Shape Distribution Size Distribution Transmission Electron Microscopy

  More +
• ISSN:
  0026-1394
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Kentucky ; OSHA Region 3 ; OSHA Region 4 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  RHD - Respiratory Health Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  254-267
• Volume:
  55
• Issue:
  2
• NIOSHTIC Number:
  nn:20051428
• Citation:
  Metrologia 2018 Feb; 55(2):254-267
• Contact Point Address:
  Eric A Grulke, Chemical and Materials Engineering, University of Kentucky, Lexington, KY, United States of America
• Email:
  eric.grulke@uky.edu
• Federal Fiscal Year:
  2018
• Peer Reviewed:
  True
• Source Full Name:
  Metrologia
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:1551292cda08e614d5666acef60a6ca30d0e25e4c506345208c54ee2608b01ecfdd979d8bdd10f4ad94277efc9a261b107711f141d2869cc6c62341c79256c2d
• Download URL:
  https://stacks.cdc.gov/view/cdc/211392/cdc_211392_DS1.pdf
• File Type:
  [PDF - 1.96 MB ]