Traumatic Exposures, Posttraumatic Stress Disorder, and Cognitive Functioning in World Trade Center Responders

Details

• Personal Author:
  Bromet EJ ; Clouston SAP ; Deri Y ; Kotov R ; Luft BJ ; Mukherjee S ; Pietrzak RH ; Richards M ; Scott SB ; Spiro A III ; Stewart C
• Description:
  Introduction: This study examined whether World Trade Center (WTC)-related exposures and posttraumatic stress disorder (PTSD) were associated with cognitive function and whether WTC responders' cognition differed from normative data. Methods: A computer-assisted neuropsychological battery was administered to a prospective cohort study of 1193 WTC responders with no history of stroke or WTC-related head injuries. Data were linked to information collected prospectively since 2002. Sample averages were compared to published norms. Results: Approximately 14.8% of sampled responders had cognitive dysfunction. WTC responders had worse cognitive function compared to normative data. PTSD symptom severity and working >5 weeks on-site was associated with cognitive dysfunction. Discussion: Results from this sample highlight the potential for WTC responders to be experiencing an increased burden of cognitive dysfunction and linked lowered cognitive functioning to physical exposures and to PTSD. Future research is warranted to understand the extent to which cognitive dysfunction is evident in neural dysfunction. [Description provided by NIOSH]
• Subjects:
  Emergency Responders Occupational Health Safety September 11 Terrorist Attacks
• Keywords:
  Author Keywords: World Trade Center Cognitive Dysfunction Emergency Responders First Responders Particulate Exposure Post-traumatic Stress Disorder Posttraumatic Stress Disorder PTSD Rescue Workers Trauma World Trade Center WTC

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• ISSN:
  2352-8737
• Document Type:
  Text
• Funding:
  Contract
• Genre:
  Journal Article
• Place as Subject:
  Connecticut ; Massachusetts ; New York ; OSHA Region 1 ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  3
• Issue:
  4
• NIOSHTIC Number:
  nn:20050844
• Citation:
  Alzheimers Dement Transl Res Clin Interv 2017 Nov; 3(4):593-602
• Contact Point Address:
  Sean A. P. Clouston, Program in Public Health, Stony Brook University, Stony Brook, NY
• Email:
  sean.clouston@stonybrookmedicine.edu
• Federal Fiscal Year:
  2018
• Peer Reviewed:
  True
• Source Full Name:
  Alzheimer's & Dementia: Translational Research & Clinical Interventions
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:a1baa9106f61ec15e739075219f811c80171614f0a90b9be36537d3b509ced6800dab29a2be9c3dbf2e54fa904ef134e90d9aa65117486fc1a3a0370feff5a13
• Download URL:
  https://stacks.cdc.gov/view/cdc/211044/cdc_211044_DS1.pdf
• File Type:
  [PDF - 669.24 KB ]