Cerebral Hemodynamics and Executive Function During Exercise and Recovery in Normobaric Hypoxia

Details

• Personal Author:
  Gerhart HD ; Glickman EL ; Kim J-H ; Seo Y ; Stavres J
• Description:
  Hypoxia and exercise each exhibit opposing effects on executive function, and the mechanisms for this are not entirely clear. This study examined the influence of cerebral oxygenation and perfusion on executive function during exercise and recovery in normobaric hypoxia (NH) and normoxia (N). METHODS: There were 18 subjects who completed cycling trials in NH (12.5% FIo2) and N (20.93% FIo2). Right prefrontal cortex (PFC) oxyhemoglobin (O2Hb) and middle cerebral artery blood velocity (MCAbv) were collected during executive function challenges [mathematical processing and running memory continuous performance task (RMCPT)] at baseline, following 30 min of acclimation, during 20 min of cycling (60% V* o2max), and at 1, 15, 30, and 45 min following exercise. RESULTS: Results indicated effects of time for Math, RMCPT, and O2Hb; but not for MCAbv. Results also indicated effects of condition for O2Hb. Math scores were improved by 8.0% during exercise and remained elevated at 30 min of recovery (12.5%), RMCPT scores significantly improved at all time points (7.5-11.9%), and O2Hb increased by 662.2% and 440.9% during exercise in N and NH, respectively, and remained elevated through 15 min of recovery in both conditions. DISCUSSION: These results support the influence of PFC oxygenation and perfusion on executive function during exercise and recovery in N and NH. [Description provided by NIOSH]
• Subjects:
  Lung Lung Diseases Nervous System Occupational Health Respiratory System Respiratory Tract Diseases Safety
• Keywords:
  Altitude Author Keywords: Acute Hypoxia Cerebrovascular System Cognitive Function Hypoxia Neurological System Oxygen Delivery Physical Exercise
• ISSN:
  2375-6314
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 3 ; OSHA Region 5 ; Pennsylvania
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  NPPTL - National Personal Protective Technology Laboratory
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  88
• Issue:
  10
• NIOSHTIC Number:
  nn:20050457
• Citation:
  Aerosp Med Hum Perform 2017 Oct; 88(10):911-917
• Contact Point Address:
  Yongsuk Seo, Ph.D., Department of Exercise Physiology, Kent State University, Gym Annex 167, Kent, OH 44242
• Email:
  yseo@kent.edu
• Federal Fiscal Year:
  2018
• NORA Priority Area:
  Healthcare and Social Assistance
• Peer Reviewed:
  True
• Source Full Name:
  Aerospace Medicine and Human Performance
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:24f44bcacb80d531292b7be0414b0d77a374caeeee698ba015d591861fe0403e5fcab8e41abe5777470e233522bf1148bd8b98f55e036ba28fb2f5814423f2fe
• Download URL:
  https://stacks.cdc.gov/view/cdc/210786/cdc_210786_DS1.pdf
• File Type:
  [PDF - 753.95 KB ]