Current Intelligence Bulletin 21 – Trimellitic Anhydride (TMA)

Details

• Corporate Authors:
  National Institute for Occupational Safety and Health
• Description:
  The National Institute for Occupational Safety and Health (NIOSH) recommends that trimellitic anhydride (TMA) be handled as an extremely toxic agent in the workplace. Exposure to this compound may result in noncardiac pulmonary edema (apparently without benefit of a pulmonary irritation warning), immunological sensitization, and irritation of the pulmonary tract, eyes, nose, and skin. There is no current Occupational Safety and Health Administration (OSHA) exposure standard for trimellitic anhydride. The Amoco Chemicals Corporation, the sole domestic producer, suggests a limit of "0.05 mg/m3 or less for susceptible individuals."(1) NIOSH has prepared this Current Intelligence Bulletin to advise you of recent findings of toxic effects of trimellitic anhydride and to provide some precautions for handling trimellitic anhydride in the workplace. Attached are "Suggested Procedures for Minimizing Employees' Exposure to Trimellitic Anhydride." [Description provided by NIOSH]
• Subjects:
  Anhydrides Hazardous Substances Occupational Health Safety Toxicology
• Keywords:
  Curing-agents Exposure-levels Health-hazards Industrial-medicine Occupational-safety Pulmonary-edema Toxic-materials
• Series:
  NIOSH Numbered Publications
• Subseries:
  Current Intelligence Bulletin
• DOI:
  https://doi.org/10.26616/NIOSHPUB78121
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Handout/Flyer
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-8
• NIOSHTIC Number:
  nn:20000335
• NTIS Accession Number:
  PB87-149274
• Citation:
  Morgantown, WV: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHEW (NIOSH) Publication No. 78-121, (CIB-21), 1978 Feb; :1-8
• CAS Registry Number:
  Trimellitic anhydride (CAS RN 552-30-7)
• Federal Fiscal Year:
  1978
• Peer Reviewed:
  False
• Source Full Name:
  National Institute for Occupational Safety and Health
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:fa65ca07fe8a2db24f289515a747588b840452f70d62a628bab39afc49601895a9b1b81957becc76d66363dc6a43957b9b2789c96277bb3e92037d957af30553
• Download URL:
  https://stacks.cdc.gov/view/cdc/209800/cdc_209800_DS1.pdf
• File Type:
  [PDF - 322.62 KB ]