Current Intelligence Bulletin 30 – Epichlorohydrin

Details

• Corporate Authors:
  National Institute for Occupational Safety and Health
• Description:
  The National Institute for Occupational Safety and Health (NIOSH) recommends that as a prudent measure, epichlorohydrin be handled in the workplace as if it were a human carcinogen. This recommendation is based primarily on two recent studies: a long term epidemiologic study showing significant increase in respiratory cancer deaths of exposed workers, and an inhalation study showing an increase in nasal carcinomas in rats. In addition, cytogenic studies of human peripheral lymphocytes have shown a highly significant increase in chromosome abnormalities in exposed workers. Pending further evaluation of its carcinogenic potential, NIOSH believes it would be prudent to minimize occupational exposure to epichlorohydrin. NIOSH has prepared this Bulletin to advise you of these recent studies, their implications for occupational health, and precautions for handling products containing epichlorohydrin. We request that producers, distributors, and users transmit this information to their customers and employees, and that professional associations and unions inform their members. [Description provided by NIOSH]
• Subjects:
  Carcinogens Environmental Exposure Hazardous Substances Insecticides Laboratories Occupational Health Safety
• Keywords:
  Drugs Exposure Levels Hazardous Materials Humans Industrial Medicine Laboratory Animals Occupational Safety Programs Pesticides Toxic Materials
• Series:
  NIOSH Numbered Publications
• Subseries:
  Current Intelligence Bulletin
• DOI:
  https://doi.org/10.26616/NIOSHPUB79105
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Handout/Flyer
• Place as Subject:
  Maryland ; OSHA Region 3
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DCDSD - Division of Criteria Documents and Standards Development
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-13
• NIOSHTIC Number:
  nn:20000303
• NTIS Accession Number:
  PB85-119147
• Citation:
  Rockville, MD: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHEW (NIOSH) Publication No. 79-105, (CIB 30), 1978 Oct; :1-13
• CAS Registry Number:
  Epichlorohydrin (CAS RN 106-89-8)
• Federal Fiscal Year:
  1979
• Peer Reviewed:
  False
• Source Full Name:
  National Institute for Occupational Safety and Health
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:c8b8a3a4cd349281d1ba0c058506219bf7f5e371ff554001275ac4e80d69fa0df6c7176a2f6f70b81655f4baac88dd1cd12d198a395501439bd55e07777b7cb6
• Download URL:
  https://stacks.cdc.gov/view/cdc/209785/cdc_209785_DS1.pdf
• File Type:
  [PDF - 3.37 MB ]