NEG and NIOSH Basis for an Occupational Health Standard: Ethyl Ether

Details

• Personal Author:
  Arvidson, Björn
• Description:
  Possible health hazards resulting from occupational exposure to ethyl-ether (60297) were reviewed and discussed. Topics included physical properties, chemical properties, industrial uses, occupational exposures, toxicokinetics, acute toxicity, chronic toxicity, organ system effects, immunotoxicity, mutagenicity, genotoxicity, carcinogenicity, reproductive toxicity, dose/response relationships, and research needs. Studies have indicated that the acute and chronic toxicity of the ethyl-ether is low. Inhalation and skin absorption have been the most important routes of occupational exposure. Upper respiratory tract irritation is the critical effect which should be taken into consideration when setting an occupational exposure limit. Nasal irritation has been reported at 200 parts per million. Chronic exposure to low concentrations of ethyl-ether in air may produce central nervous system symptoms, including sleepiness, dizziness, irritability, headache, and psychic disturbances. Ethyl-ether was found to be a mild skin irritant with repeated exposures. [Description provided by NIOSH]
• Subjects:
  Hazardous Substances Irritants Occupational Exposure Occupational Health Safety Skin Solvents
• Keywords:
  Acute-toxicity Chronic-toxicity Occupational-exposure Organic-solvents Respiratory-irritants Skin-irritants Solvent-vapors Toxic-effects
• Series:
  NIOSH Numbered Publications
• DOI:
  https://doi.org/10.26616/NIOSHPUB93103
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Standards
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSDTT - Division of Standards Development and Technology Transfer
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-45
• NIOSHTIC Number:
  nn:00213113
• NTIS Accession Number:
  PB93-189140
• Citation:
  Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 93-103, 1993 Feb; :1-45
• CAS Registry Number:
  Diethyl ether (CAS RN 60-29-7)
• Federal Fiscal Year:
  1993
• Peer Reviewed:
  False
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7df6becc891cfc83d6ce99bcbf95ac91d38285995c80e5ce6bc436dcdabfdd94f1127ecd60d171acf327a234cd506697543e2bba8d68d95c951da3eb8e77d8f0
• Download URL:
  https://stacks.cdc.gov/view/cdc/209637/cdc_209637_DS1.pdf
• File Type:
  [PDF - 2.17 MB ]