NEG and NIOSH Basis for an Occupational Health Standard: Propylene Glycol Ethers and Their Acetates

Details

• Personal Author:
  Johansson G
• Description:
  The propylene glycol ethers and their acetates were reviewed as background for discussion of occupational exposure limits. The most commonly used propylene glycols in industry were 1-methoxy-2- propanol (107982), 2-methoxy-1-propanol (1320678), 1-methoxy-2- propyl-acetate (108656), 2-methoxy-1-propyl-acetate (70657704) and dipropylene-glycol-monomethyl-ether (34590948). The report included information concerning ambient air levels at the workplace, analytical methods for air monitoring, toxicokinetics (uptake, probably routes of human exposure, distribution, biotransformation, elimination, and biological exposure indicators), general toxicology (toxic mechanisms and in-vitro studies, factors influencing toxicity, and general effects), organ effects (skin and mucous membranes, respiratory system, liver, kidneys, gastrointestinal tract, circulatory system, hematological system, central nervous system, and peripheral nervous system), immunotoxicity and allergy, mutagenicity, genotoxicity, carcinogenicity, reproductive toxicity, dose effect and dose response relationships (short term exposure, and long term exposure), and research needs. [Description provided by NIOSH]
• Subjects:
  Environmental Monitoring Hazardous Substances Occupational Exposure Occupational Health Safety Solvents
• Keywords:
  Air-quality-monitoring Analytical-methods Biological-effects Gene-mutation Genotoxic-effects Health-standards Occupational-exposure Organic-solvents Solvent-vapors Toxic-effects
• Series:
  NIOSH Numbered Publications
• DOI:
  https://doi.org/10.26616/NIOSHPUB91103
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Standards
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSDTT - Division of Standards Development and Technology Transfer
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-53
• NIOSHTIC Number:
  nn:00199715
• NTIS Accession Number:
  PB91-220749
• Citation:
  Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 91-103, 1991 Jan; :1-53
• CAS Registry Number:
  1-Methoxy-2-propanol (CAS RN 107-98-2) ; 1-Methoxy-2-propyl acetate (CAS RN 108-65-6) ; 1-Propanol, 2-methoxy-, 1-acetate (CAS RN 70657-70-4) ; Dipropylene glycol monomethyl ether (CAS RN 3454,4′-Bis(dimethylamino)benzophenone (CAS RN 90-94-8)) ; Propylene glycol monomethyl ether (CAS RN 1320-67-8)
• Federal Fiscal Year:
  1991
• Peer Reviewed:
  False
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:b8c7ce316f70b576fdc5132a3ae52ca04eed6cdb62f981e4c06764f431abfc9a9ca3890744f6bb036bd17f06dd4bf8e8918980b842fb8d22aaf73139e6ccf676
• Download URL:
  https://stacks.cdc.gov/view/cdc/209621/cdc_209621_DS1.pdf
• File Type:
  [PDF - 2.47 MB ]