Current Intelligence Bulletin 15 – Nitrosamines in Cutting Fluids

Details

• Corporate Authors:
  National Institute for Occupational Safety and Health
• Description:
  The hazard associated with nitrosamines in cutting fluids was discussed. A study confirming the presence of diethanolnitrosamine (1116547) (DENA) in samples of commercial cutting fluids produced by four randomly selected companies is summarized. During an actual machining operation, 1000 parts per million (ppm) DENA were found in the cutting fluid before use and 384ppm after use, suggesting exposure of machine operators to the nitrosamine. An epidemiologic study reported a slight, nonsignificant excess of mortality from respiratory tract and digestive system cancers among male workers exposed to cutting fluids in metal machine jobs. The four categories of commercial cutting fluids were presented. NIOSH estimated that 780,000 persons were occupationally exposed during manufacture and use of cutting fluids. Recommendations for reducing dermal and respiratory exposure to cutting fluids are given. These include using local exhaust ventilation, substitution with a cutting fluid that does not contain nitrosamines or the ingredients for nitrosamine formation where feasible, using chemically impervious clothing and barrier creams, and cleansing any area that becomes wet with cutting fluids. It is noted that NIOSH is planning industrial hygiene and epidemiologic studies of nitrosamine exposure and carcinogenesis bioassays. [Description provided by NIOSH]
• Subjects:
  Amines Hazardous Substances Manufacturing And Industrial Facilities Neoplasms Occupational Exposure Occupational Health Personal Protective Equipment Risk Assessment Risk Factors Safety
• Keywords:
  Cancer Cutting-oils Health-hazards Machinists NIOSH-Author NIOSH-Current-Intelligence-Bulletin-No-15 Nitroso-compounds Occupational-exposure Protective-measures Risk-analysis Risk-factors

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• Series:
  NIOSH Numbered Publications
• Subseries:
  Current Intelligence Bulletin
• DOI:
  https://doi.org/10.26616/NIOSHPUB7812715
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Handout/Flyer
• Place as Subject:
  Maryland ; OSHA Region 3
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DCDSD - Division of Criteria Documents and Standards Development
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-4
• NIOSHTIC Number:
  nn:00170796
• NTIS Accession Number:
  PB83-105080
• Citation:
  Rockville, MD: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHEW (NIOSH) Publication No. 78-127, (CIB 15), 1976 Oct; :1-4
• CAS Registry Number:
  N-Nitrosodiethanolamine (CAS RN 1116-54-7)
• Federal Fiscal Year:
  1977
• Peer Reviewed:
  False
• Source Full Name:
  National Institute for Occupational Safety and Health
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:b36aff53ba6f4c2411c2ad5dc055867d2dad07659242b1c900151dd5934b1ebbeddaa4b2ca060f83ac8339c5adc0ad23c20bf107abf8931f3a558dbd9d51e0f0
• Download URL:
  https://stacks.cdc.gov/view/cdc/209490/cdc_209490_DS1.pdf
• File Type:
  [PDF - 608.85 KB ]