Carcinogenicity and Metabolism of Azo Dyes, Especially Those Derived from Benzidine

Details

• Personal Author:
  Boeniger, Mark F.
• Description:
  The carcinogenicity and metabolism of azo dyes derived from benzidine (92875) is presented. The metabolism of benzidine and azo compounds in humans and animals is discussed, and the disease incidence among workers in industries using azo dyestuffs is described. Industrial hygiene surveys performed to monitor the environment of azo dye workers and their urinary excretion of aromatic amines and benzidine are reviewed. Jobs involving dyestuff exposure and exposure to carcinogenic agents are identified. The author concludes that this study indicates the potential carcinogenicity of benzidine and the metabolites of benzidine derived dyes. [Description provided by NIOSH]
• Subjects:
  Biochemistry Coloring Agents Energy Metabolism Environmental Monitoring Occupational Exposure Occupational Health Polycyclic Aromatic Hydrocarbons Safety
• Keywords:
  Air-sampling Aromatic-hydrocarbons Azo-dyes Industrial-hygiene Metabolism NIOSH-Author Occupational-exposure Oncogenesis
• Series:
  NIOSH Numbered Publications
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Report
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-141
• NIOSHTIC Number:
  nn:00103469
• NTIS Accession Number:
  PB81-171027
• Citation:
  Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 80-119, 1980 Jul; :1-141
• CAS Registry Number:
  4,4'-Diaminodiphenyl (CAS RN 92-87-5)
• Federal Fiscal Year:
  1980
• Peer Reviewed:
  False
• Source Full Name:
  National Institute for Occupational Safety and Health
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:eb8a498adbb8a2fe630c8f2d3cbb48c93ab3fc9bff03cf3929fa40ed7a28c614a09eca286dafe18d6ca0064467be5c291e173d0ae88f01e5bb32d934a344ce00
• Download URL:
  https://stacks.cdc.gov/view/cdc/209396/cdc_209396_DS1.pdf
• File Type:
  [PDF - 3.89 MB ]