Special Occupational Hazard Review of Trichloroethylene

Details

• Personal Author:
  Arthur, Jack L. ; Page, Norbert P.
• Description:
  A brief description is provided of the production, uses, toxicity, and metabolism of trichloroethylene (79016) (TCE), and a special occupational hazard review is given of TCE's potential as a workplace carcinogen. In addition, the results of a recent survey of industrial vapor degreasing operations, the primary source of occupational exposures to TCE, are presented along with data from other surveys or reviews to document the extent and nature of occupational exposures to TCE and existing control methods. TCE's acute toxicity is well known and is related mainly to central nervous system depression, cardiac arrhythmias, and dermal effects. In contrast, chronic effects are not so well documented under usual occupational exposure conditions. There is evidence, however, for latent effects, including those of the liver, kidneys, and nervous system. Based upon this special review of all these data, NIOSH concludes that TCE has a weak carcinogenic potential. [Description provided by NIOSH]
• Subjects:
  Carcinogens Chlorine Compounds Hydrocarbons Nervous System Nervous System Diseases Occupational Health Safety Sense Organs Solvents Toxicology
• Keywords:
  Carcinogenesis Chlorinated-ethylenes Chlorinated-hydrocarbons Nervous-system-disorders Neurological-diseases NIOSH-Author NIOSH-Criteria-Document Organic-solvents Physiological-function Sensory-disorders
• Series:
  NIOSH Numbered Publications
• DOI:
  https://doi.org/10.26616/NIOSHPUB78130
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Standards
• Place as Subject:
  Maryland ; OSHA Region 3
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DCDSD - Division of Criteria Documents and Standards Development
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-89
• NIOSHTIC Number:
  nn:00080192
• NTIS Accession Number:
  PB81-226987
• Citation:
  Rockville, MD: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHEW (NIOSH) Publication No. 78-130, 1978 Jan; :1-89
• CAS Registry Number:
  Trichloroethylene (CAS RN 79-01-6)
• Federal Fiscal Year:
  1978
• Peer Reviewed:
  False
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:2097d54f1b032a04c09771ca89dfa834e972b278e2e50cab8d08c6bac2377b98729d766a6a5a0c5551b963563f013929821a1200e2862e47744db3b1c93bd287
• Download URL:
  https://stacks.cdc.gov/view/cdc/209326/cdc_209326_DS1.pdf
• File Type:
  [PDF - 4.49 MB ]