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Acute Symptoms and Exposure to Hydrogen Peroxide, Acetic Acid and Peracetic Acid in Hospital Cleaning Staff

Public Domain


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  • Personal Author:
  • Description:
    Objective: Current CDC guidance for the disinfection of gloved hands during personal protective equipment doffing following care of a patient with Ebola allows for multiple applications of alcohol-based hand rub (ABHR) on medical exam gloves. The purpose of this study was to evaluate the effect of ABHR treatments on glove integrity based on changes in tensile properties. Methods: Thirteen brands of medical exam gloves (8 brands of nitrile and 5 brands of latex from 5 manufacturers), and two different ABHRs containing 70% ethanol and 63% isopropanol, respectively, were included in this study. For each brand, 140 gloves were tested. Thicknesses of the new gloves measured in the palm areas ranged from 0.129 to 0.226 mm among 700 latex gloves and 0.057 to 0.143 mm among 1120 nitrile gloves. A pair of gloves were worn by a test operator and outside surfaces of the gloves were treated with either ABHR for 1 to 6 treatments. Ultimate tensile strength and elongation of the gloves without ABHR treatment and after 1 to 6 treatments were measured based on ASTM D412 standard method by using an Instron Universal Testing Machine with a 500N load cell. Ten replicates were performed and analysis of variance was used for statistical comparison. Results: Compared to gloves without ABHR treatment, mean tensile strength of the 5 brands of latex gloves decreased 4.3% (p > 0.05) after 6 ABHR treatments using ethanol-based hand rub (EBHR) and 18% (p < 0.05) using isopropanol-based hand rub (IBHR). Mean elongation increased 2% (p > 0.05) and decreased 2% (p > 0.05) after 6 treatments using EBHR and IBHR, respectively. For the 8 brands of nitrile gloves after 6 treatments, mean tensile strength decreased 26% (p < 0.05) using EBHR and 36% using IBHR (p < 0.05). Mean elongation increased 1.7% (p > 0.05) using EBHR and 4.8% (p < 0.05) using IBHR after 6 treatments. It appeared that changes in the tensile properties increased with each ABHR application. For instance, mean decreases of the tensile strength for the nitrile gloves after 3 and 4 EBHR treatments were 14% and 18% respectively. Conclusions: The preliminary results indicate that ABHRs had more effect on tensile strength of the tested nitrile than latex gloves. In general, EBHR resulted in lesser changes in tensile strength compared to IBHR. Nevertheless, after up to 6 treatments all tested gloves still met NFPA 1999 glove requirements for tensile strength = 14 MPa and elongation = 500%, except for two brands of relatively thin gloves (0.059 and 0.087 mm), 15% of the 13 brands tested. [Description provided by NIOSH]
  • Subjects:
  • Keywords:
  • Publisher:
    American Industrial Hygiene Association
  • Document Type:
    Text
  • Genre:
    Abstract or Summary
  • Place as Subject:
  • CIO:
    National Institute for Occupational Safety and Health (NIOSH)
  • Division:
    NPPTL - National Personal Protective Technology Laboratory
  • Topic:
    Workplace Safety & Health
  • Location:
    North America
  • Pages in Document:
    46-47
  • NIOSHTIC Number:
    nn:20065992
  • Citation:
    AIHce 2016: American Industrial Hygiene Conference and Exposition Pathways to Progress, May 21-26, 2016, Baltimore, Maryland. Falls Church, VA: American Industrial Hygiene Association, 2016 May; :46-47
  • Contact Point Address:
    P. Gao, CDC/NIOSH, Pittsburgh, PA
  • Federal Fiscal Year:
    2016
  • Peer Reviewed:
    False
  • Source Full Name:
    AIHce 2016: American Industrial Hygiene Conference and Exposition Pathways to Progress, May 21-26, 2016, Baltimore, Maryland
  • Collection(s):
  • Main Document Checksum:
    urn:sha-512:bdf45b2a18f9fa9ada1161a786524993a3b262f7c0014ddfd2ba622b1e9f7a1e2821631a41ec9060712d4e281280685fdc5cbcb0992bbcffdac251540739cf95
  • Download URL:
  • File Type:
    Filetype[PDF - 1.44 MB ]
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