Onion Consumption Is Protective Against Asthma Risk in Children: ROAD to Health Population-Based Cohort Study

Details

• Personal Author:
  Nolan A ; Norweg A ; Oh C
• Description:
  Asthma is an inflammatory, heterogeneous lung disease with airway obstruction, hyperresponsiveness to allergens, and wheezing. The etiology of asthma involves multifactorial underlying mechanisms and inflammatory pathways. There is an unmet, urgent need to identify effective treatments for prevention of asthma. Quercetin-rich apples and onions may be medicinal foods associated with reduced risk of asthma. Quercetin is a major dietary polyphenol flavonoid shown to have anti-inflammatory, antioxidant, and antiviral activity involved in asthma disease development. Animal studies support a therapeutic role of quercetin in lung health. Apples and onions may also play a protective role in increasing microbiota diversity, immunoregulation, and immune maturation in childhood to prevent asthma development. The study aims were to examine the relationship between apple and onion consumption and asthma prevalence and to explore any moderating effect of age. We hypothesized that more frequent apple and onion consumption are associated with reduced odds of prevalent asthma and that age moderates this relationship. [Description provided by NIOSH]
• Subjects:
  Asthma Asthma, Occupational Cohort Studies Diet Occupational Health Respiratory System Respiratory Tract Diseases Safety
• Keywords:
  Children Cohort Studies Population Based Studies Respiratory Diseases
• ISSN:
  0954-6111
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  New York ; New York City Region [OSHA]
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  233
• NIOSHTIC Number:
  nn:20070819
• Citation:
  Respir Med 2024 Nov; 233:107767
• Email:
  anna.norweg@mssm.edu
• Federal Fiscal Year:
  2025
• Performing Organization:
  New York University School of Medicine
• Peer Reviewed:
  False
• Start Date:
  20210701
• Source Full Name:
  Respiratory Medicine
• End Date:
  20260630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:520e3c32d5dabc37686d0234052693c51a8b71c843bbb595248bf2a6f777bc69b439f123e801549e7b84cc248c584668a955aef6307bb8af1222544e54a2c507
• Download URL:
  https://stacks.cdc.gov/view/cdc/208968/cdc_208968_DS1.pdf
• File Type:
  [PDF - 381.22 KB ]