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Association of PTSD History with Confusion or Memory Loss Among World Trade Center Health Registry Enrollees



Details

  • Personal Author:
  • Description:
    Background: Burgeoning research suggests that people exposed to the 9/11/2001 terrorist attacks in New York City (NYC) may be at greater risk for cognitive impairment due to a variety of potential exposures. We investigated whether posttraumatic stress disorder (PTSD) history was associated with self-reported confusion or memory loss (CML) among World Trade Center Health Registry enrollees. Methods: The study sample included enrollees who completed all five wave surveys (W1 in 2003-04 through W5 in 2020-21), were between the ages of 35 and 64 during W3-W5, and had no history of stroke or dementia (N = 11,432). We categorized PTSD history during W1-W3 as chronic-high, increased, decreased, or resilient-low with trajectory analysis. Generalized estimating equations modeling was used for the repeated measures analysis of the outcome, CML. Results: Compared to those in the resilient-low PTSD group, those in the decreased and increased PTSD groups were at over 52% greater risk of reporting CML; those in the chronic-high PTSD group had between a 1.62 and 1.92 times greater risk of CML than the resilient-low PTSD group, with non-rescue/recovery workers having greater risk on average. PTSD history was also associated with elevated risk of more severe CML-related outcomes in W5 - specifically, experiencing worsening symptoms and functioning in daily life. Limitations: CML symptoms are self-reported, and generalizability of results may be limited. Conclusions: These findings suggest that survivors with PTSD should be monitored for cognitive issues, including CML. Effective treatment of PTSD may have benefits beyond mitigation of PTSD symptoms. [Description provided by NIOSH]
  • Subjects:
  • Keywords:
  • ISSN:
    2666-9153
  • Document Type:
    Text
  • Funding:
    Cooperative Agreement
  • Genre:
    Journal Article
  • Place as Subject:
  • CIO:
    National Institute for Occupational Safety and Health (NIOSH)
  • Topic:
    Workplace Safety & Health
  • Location:
    North America
  • Volume:
    14
  • NIOSHTIC Number:
    nn:20068607
  • Citation:
    J Affect Disord Rep 2023 Dec; 14:100655
  • Contact Point Address:
    Kacie Seil, New York City Department of Health and Mental Hygiene, Division of Epidemiology, 125 Worth Street, New York, NY 10013, United States
  • Email:
    kseil@health.nyc.gov
  • Federal Fiscal Year:
    2024
  • Performing Organization:
    New York City Health/Mental Hygiene
  • Peer Reviewed:
    True
  • Start Date:
    20090430
  • Source Full Name:
    Journal of Affective Disorders Reports
  • End Date:
    20260630
  • Collection(s):
  • Main Document Checksum:
    urn:sha-512:b0119e876b45c17d545f2fa572ddd6af69ede31ad469143ef13fac6da78b7ba5b012357008ae4ca401b8fad485bdd85949a12f6b651c49319431034f3af3d7ae
  • Download URL:
  • File Type:
    Filetype[PDF - 459.07 KB ]
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