The mutagenicity of electrocautery smoke

Details

• Personal Author:
  Bryant, Charles J. ; Gatti JE ; Murphy JB ; Noone RB
• Description:
  The mutagenicity of airborne smoke particles generated from the use of electrocautery knives during surgical procedures was studied. Air samples were collected on filters in two operating rooms during routine reduction mammoplasties involving extensive use of electrocautery knives. The samples were extracted and tested for mutagenic activity using the Salmonella microsomal microsuspension test with both (TA-98) and (TA-100) strains. After exposure to the smoke extracts, alteration of histidine dependence was seen in strain (TA-98). Samples extracted with methylene-chloride showed higher mutagenicity than those extracted using an XAD-2 column. The extracts had no effect on strain (TA-100) in mutagenicity tests. Some differences were seen in extracts obtained from different patients. No effects were seen after waiting 2 hours or more after surgery before extracting and testing the samples. The authors recommend the development of techniques to limit the exposure of operating room personnel to smoke from electrocautery knives. [Description provided by NIOSH]
• Subjects:
  Aerosols Air Pollutants, Occupational Air Pollution, Indoor Environmental Monitoring Health Care Facilities Workforce And Services Health Personnel Mutagens Occupational Exposure Occupational Health Safety
• Keywords:
  Aerosol-particles Air-contamination Air-samples Health-care-personnel Medical-equipment Microbial-test-systems NIOSH-Author Occupational-exposure
• ISSN:
  0032-1052
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  New Jersey ; Ohio ; OSHA Region 2 ; OSHA Region 3 ; OSHA Region 5 ; Pennsylvania
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  89
• Issue:
  5
• NIOSHTIC Number:
  nn:00207009
• Citation:
  Plast Reconstr Surg 1992 May; 89(5):781-784
• Federal Fiscal Year:
  1992
• Peer Reviewed:
  True
• Source Full Name:
  Plastic and Reconstructive Surgery
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:247ec349e85cc6678d85dff2e1c98c85d1c9472b23d82b74aeeff1d03c2f0e70ddc31f0d48a60d1b81831da984fb02721e083371b16c8c110026d6468fa1490b
• Download URL:
  https://stacks.cdc.gov/view/cdc/205747/cdc_205747_DS1.pdf
• File Type:
  [PDF - 281.52 KB ]