Respiratory cancer and other chronic disease mortality among silicotics in California

Details

• Personal Author:
  Beaumont, James J. ; Goldsmith DF ; Morrin LA ; Schenker MB
• Description:
  An epidemiological study was conducted on mortality risks associated with silicosis. Mortality rates were calculated for 590 cases of silicosis identified from a registry of Workers' Compensation Appeals Board Claimants for the period 1945 to 1975. State vital records were used to determine mortality risks to 1991. The well recognized association between silicosis and increased mortality due to tuberculosis and other nonmalignant respiratory diseases was confirmed in this analysis. The standardized mortality ratio (SMR) for tuberculosis was 56.34; the SMR for nonmalignant respiratory disease was 3.80. A significantly increased risk for all causes of death was seen among the cohort, along with increased SMRs cirrhosis of the liver, and for cancers of the trachea, bronchus, and lung. The SMR for cancer of the large intestine was 2.08. Significantly decreased SMRs were seen for cardiovascular diseases, as well as cancers of the prostate and lymphatic system. The authors conclude that patients with silicosis should be educated about these associated disease risks. [Description provided by NIOSH]
• Subjects:
  Digestive System Digestive System Diseases Lung Diseases Mortality Neoplasms Occupational Exposure Occupational Health Respiratory Tract Diseases Safety Silicon Dioxide
• Keywords:
  Cancer-rates Gastrointestinal-system-disorders Lung-disease Mortality-rates NIOSH-Cooperative-Agreement NIOSH-Grant NIOSH-Publication Occupational-exposure Pulmonary-system-disorders Silica-dusts
• ISSN:
  0271-3586
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  459-467
• Volume:
  28
• Issue:
  4
• NIOSHTIC Number:
  nn:00229159
• Citation:
  Am J Ind Med 1995 Oct; 28(4):459-467
• Contact Point Address:
  Internal Medicine University of California Internal Medicine Davis, CA 95616
• Federal Fiscal Year:
  1996
• NORA Priority Area:
  Pulmonary System Disorders
• Performing Organization:
  University of California Davis, Davis, California
• Peer Reviewed:
  True
• Start Date:
  19890601
• Source Full Name:
  American Journal of Industrial Medicine
• End Date:
  19931130
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:a62c5d7cd45516c5393e1128410619309ec1f6bb3526a37ec486f71f135f9ba545ee758346ef3ea8285743776623b676079e1c692012fb701c2204bb7e41da7f
• Download URL:
  https://stacks.cdc.gov/view/cdc/205504/cdc_205504_DS1.pdf
• File Type:
  [PDF - 698.43 KB ]