Recent studies of temporary threshold shift (TTS) and permanent threshold shift (PTS) in animals

Details

• Personal Author:
  Clark WW
• Description:
  A review was presented to describe the major observations obtained from laboratory studies of experimentally induced hearing losses, both temporary and permanent, resulting from exposure to noise in animal subjects. Studies that measured hearing directly were given the greatest weight in the review. The data evaluated supported several general conclusions. The chinchilla was the most widely used and most appropriate animal model for studies of noise induced hearing loss. With continuous exposures to moderate level noise, thresholds reached asymptotic levels within 18 to 24 hours. Permanent threshold shifts, however, depended upon the level, frequency, and the duration of exposure. Below a critical level of about 115 decibels, permanent threshold shift and cell loss were generally related to the total energy in continuous exposures. Periodic rest periods inserted in an exposure schedule were predictive and resulted in less hearing loss and cochlear damage than equal energy continuous exposures. Under some schedules of periodic exposure, threshold shifts increased over the first few days of exposure, then recovered as much as 30 decibels as the exposure continued. [Description provided by NIOSH]
• Subjects:
  Acoustics Ear Hearing Loss Hearing Loss, Noise-Induced Noise Occupational Health Safety Sense Organs
• Keywords:
  Acoustic-vibration Acoustical-measurements Ear-disorders Hearing-impairment Hearing-loss NIOSH-Grant NIOSH-Publication Noise-exposure Noise-induced-hearing-loss Sensory-thresholds
• ISSN:
  0001-4966
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Missouri ; OSHA Region 7
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  155-163
• Volume:
  90
• Issue:
  1
• NIOSHTIC Number:
  nn:00201932
• Citation:
  J Acoust Soc Am 1991 Jul; 90(1):155-163
• Contact Point Address:
  Research Central Inst for the Deaf 818 South Euclid St Louis, MO 63110
• Federal Fiscal Year:
  1991
• NORA Priority Area:
  Disease and Injury: Hearing Loss
• Performing Organization:
  Central Institute for the Deaf, Saint Louis, Missouri
• Peer Reviewed:
  True
• Start Date:
  19840901
• Source Full Name:
  Journal of the Acoustical Society of America
• End Date:
  19991130
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:936e1b80984e99bcb2166e7860834cfe5c652878a5863f0625e8f7ac884a1d95d814bd3a901a4f9bef4cb1fa4c1b3a0881512c261d7c76925dddbe3bdbc7a8ff
• Download URL:
  https://stacks.cdc.gov/view/cdc/205465/cdc_205465_DS1.pdf
• File Type:
  [PDF - 2.90 MB ]