Radon-exposed underground miners and inverse dose-rate (protraction enhancement) effects

Details

• Personal Author:
  Boice JD Jr. ; Edling C ; Hornung, Richard W. ; Howe G ; Kunz E ; Kusiak RA ; Lubin JH ; Morrison HI ; Radford EP ; Samet JM ; Tirmarche M ; Woodward A ; Yao SX
• Description:
  The data from 11 studies of underground radon (10043922) exposed miners, which included 2,701 lung cancer deaths and 1.2 million person years of observation, were analyzed with respect to the existence of the inverse dose rate (protraction enhancement) effect and the diminution of the effect at low total dose. Data from the studies provided evidence of a protraction enhancement effect for high linear energy transfer (LET) radiation. It was stated that for high LET radiation at low total dose, there is a low probability of more than one alpha particle traversing a cell, and therefore, the inverse dose rate should decrease. The results of the data analyses supported this assertion for exposures under 50 Working Level Months. The authors conclude that in using miner based models for estimating radon effects in homes, where durations of exposure are longer and radon progeny concentrations lower despite the lower cumulative exposures, the inverse dose rate effect and its diminution at low rates should be considered. [Description provided by NIOSH]
• Subjects:
  Epidemiology Lung Lung Diseases Mining Neoplasms Occupational Health Radiation Radon Respiratory System Respiratory Tract Diseases Risk Assessment Safety Workplace

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• Keywords:
  Author Keywords: Radon Cancer Lungs, Human NIOSH-Author Pulmonary-cancer Radiation-exposure Radon-daughters Risk-analysis Statistical-analysis Underground-miners Workplace-studies

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• ISSN:
  0017-9078
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Maryland ; Ohio ; OSHA Region 3 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  494-500
• Volume:
  69
• Issue:
  4
• NIOSHTIC Number:
  nn:00229839
• Citation:
  Health Phys 1995 Oct; 69(4):494-500
• CAS Registry Number:
  Radon (CAS RN 10043-92-2)
• Federal Fiscal Year:
  1996
• Peer Reviewed:
  True
• Source Full Name:
  Health Physics
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:72e6068603a8a9257c148d1e523c6bddd0a7c661650e8e3d9d5ab3cda444634df02bcb35ca62de1d5d3b4a5c725fd8bd650d092d9941510fcca4d4b42852581a
• Download URL:
  https://stacks.cdc.gov/view/cdc/205453/cdc_205453_DS1.pdf
• File Type:
  [PDF - 200.05 KB ]