Mica-associated pulmonary interstitial fibrosis

Details

• Personal Author:
  Landas SK ; Schwartz DA
• Description:
  A case report of severe interstitial fibrosis in a 65 year old male nonsmoker who had been exposed to mica (12001262) while employed in the rubber industry was presented. A slow progression of dyspnea and development of a dry cough occurred prior to a chest radiograph which revealed marked interstitial fibrosis particularly in the right lung. The patient had worked in a rubber plant for 40 years and for a 5 year period during that time worked in the core department where he shoveled mica and was exposed to visible clouds of mica dust. The patient has undergone pulmonary function testing, high resolution chest computed tomography scanning, bronchoscopy, and lung biopsy. Elemental and crystallographic analyses indicated that mica was present in the alveoli and lung parenchyma. The patient has since been put on a steroid for increasing dyspnea and receives supplemental oxygen. The causal relationship between mica and the interstitial fibrosis was supported by the prolonged exposure to mica, absence of asbestos and other silicates, clinical and radiographic features of severe interstitial fibrosis, and histopathologic delineation of the interstitial lesion including spectroscopic and crystallographic verification of crystalline mica. [Description provided by NIOSH]
• Subjects:
  Case Reports Dust Lung Lung Diseases Occupational Exposure Occupational Health Respiratory Function Tests Respiratory System Respiratory Tract Diseases Rubber Safety

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• Keywords:
  Case-studies Humans Lung-disease Lung-fibrosis Mineral-dusts NIOSH-Grant Occupational-exposure Pulmonary-function-tests Rubber-workers
• ISSN:
  0003-0805
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Iowa ; OSHA Region 7
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  144
• Issue:
  3
• NIOSHTIC Number:
  nn:00203482
• Citation:
  Am Rev Respir Dis 1991 Sep; 144(3)(Pt 1):718-721
• Contact Point Address:
  Internal Medicine University of Iowa Pulmonary Disease Division Iowa City, IA 52242
• CAS Registry Number:
  Mica-group minerals (CAS RN 12001-26-2)
• Federal Fiscal Year:
  1991
• NORA Priority Area:
  Pulmonary System Disorders
• Performing Organization:
  University of Iowa, Iowa City, Iowa
• Peer Reviewed:
  True
• Start Date:
  19900701
• Source Full Name:
  American Review of Respiratory Disease
• End Date:
  19930630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d262eefb005f5ccb5accd83321c261c2190a70a56e176ae489e6da2601bb1d69b73c0c2836e3b4126d7bacdaa3bb9e1607b6e8250c61f3b54f2bc0b7620535f3
• Download URL:
  https://stacks.cdc.gov/view/cdc/205110/cdc_205110_DS1.pdf
• File Type:
  [PDF - 487.35 KB ]