Details:

Alternative Title:
Prev Chronic Dis
Personal Author:
He, Guozhong ; Sentell, Tetine ; Schillinger, Dean ;
He, Guozhong ; Sentell, Tetine ; Schillinger, Dean ; Less -
Description:
Introduction Self-reported prediabetes and diabetes rates underestimate true prevalence, but mass laboratory screening is generally impractical for risk assessment and surveillance. We developed the Abnormal Glucose Risk Assessment-6 (AGRA-6) tool to address this problem. Methods Self-report data were obtained from the 1,887 adults (18 years or older) in the National Health and Nutrition Examination Survey (NHANES) 2005-2006 with fasting plasma glucose and oral glucose tolerance tests. We created AGRA-6 models by using logistic regression. Performance was validated with NHANES 2005-2006 data by using leave-1-out cross-validation. Standard performance characteristics (sensitivity, specificity, predictive values, area under receiver-operating characteristic curves) were assessed, as was the potential efficiency of the models to reduce laboratory testing in screening efforts. Results Performance was good for all models under testing conditions. Use of the AGRA-6 in screening efforts could reduce laboratory testing by at least 30% when sensitivity is maximized and at least 52% when sensitivity and specificity are balanced. Conclusion The AGRA-6 appears to be an effective, feasible tool that uses self-reported data compatible with the Behavioral Risk Factor Surveillance System to assess population-level prevalence, identify abnormal glucose levels, optimize screening efforts, and focus interventions to reduce the prevalence of abnormal glucose levels.
Subject:
[+]
Adolescent
Adult
Blood Glucose
Diabetes Mellitus
Humans
Models, Biological
Nutrition Surveys
Original Research
Risk Factors
Young Adult

Source:
Prev Chronic Dis. 7(2). ;
Pubmed ID:
20158962
Pubmed Central ID:
PMC2831788
Document Type:
Journal Article ;
Funding:
3U32DP922744-05W1/DP/NCCDPHP CDC HHS/United States ; UL1 RR024131/RR/NCRR NIH HHS/United States ;
3U32DP922744-05W1/DP/NCCDPHP CDC HHS/United States ; UL1 RR024131/RR/NCRR NIH HHS/United States ; Less -
Collection(s):
Preventing Chronic Disease
Main Document Checksum:
[+]
urn:sha256:a0d074da6ff1cf793d581a4623c2dc57f7a7e2596d587bcd43226d5ef923dd8c
File Type:

Supporting Files

• 	license.txt	txt
  	PCD72A34.nxml	txt

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