Covariates of human peripheral nerve function: III. Effects of reported drinking

Details

• Personal Author:
  Gerr F ; Letz R
• Description:
  The effects of reported drinking on the covariates of human peripheral nerve function were investigated in 4,132 Vietnam era veterans using data collected by the Centers for Disease Control as part of the Vietnam Experience Study. Nerve conduction velocity (NCV) and amplitude were measured in the median motor, median sensory, ulnar sensory, peroneal motor, and sural sensory nerves of the dominant limbs of each subject using antidromic stimulation and electromyography. Vibrotactile thresholds and thermal thresholds were measured from the index finger and large toe. Serum liver enzymes were estimated. Questionnaires and interviews were used to estimate alcohol consumption. Data were analyzed using general linear models. Results showed that subjects who reported drinking less than 180 drinks per month had slightly faster mean NCVs, slightly greater evoked response amplitudes, and slightly lower vibrotactile thresholds than those who drank more or did not drink at all. Those who consumed more than 179 drinks per month had slightly slower mean conduction velocities and slightly smaller mean amplitudes than the other drinking categories. There were no consistent associations observable between thermal threshold and alcohol consumption. The authors conclude that even moderately heavy drinking (up to 6 drinks per day) does not cause a slowing of NCV, lessening of the amplitude of the evoked response, or an elevation of sensory thresholds. [Description provided by NIOSH]
• Subjects:
  Alcoholic Beverages Electrophysiology Epidemiology Musculoskeletal Diseases Occupational Health Safety Surveys And Questionnaires
• Keywords:
  Alcoholic-beverages Military-personnel Musculoskeletal-system-disorders Nerve-function NIOSH-Cooperative-Agreement NIOSH-Grant NIOSH-Publication Questionnaires
• ISSN:
  0892-0362
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  113-122
• Volume:
  16
• Issue:
  1
• NIOSHTIC Number:
  nn:00219452
• Citation:
  Neurotoxicol Teratol 1994 Jan; 16(1):113-122
• Contact Point Address:
  Community Medicine Mount Sinai School of Medicine One Gustave L Levy Place New York, NY 10029
• Federal Fiscal Year:
  1994
• NORA Priority Area:
  Disease and Injury: Musculoskeletal Disorders of the Upper Extremities
• Performing Organization:
  Mount Sinai School of Medicine, New York, New York
• Peer Reviewed:
  True
• Start Date:
  19900928
• Source Full Name:
  Neurotoxicology and Teratology
• End Date:
  19930927
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:1d42341dd7a5be44b8891a17b7309f64f0af0916d82e945629a1f4fec3e11391dd14c9c3ddc126603913c5973415801e96bdbde3940576d50b9787b9fc9d1e88
• Download URL:
  https://stacks.cdc.gov/view/cdc/204422/cdc_204422_DS1.pdf
• File Type:
  [PDF - 1.02 MB ]