Comparison of serum levels of 2,3,7,8-TCDD in TCP production workers and in an unexposed comparison group

Details

• Personal Author:
  Connally LB ; Dugle JE ; Fingerhut, Marilyn A. ; Greife AL ; Halperin, William E. ; Hornung, Richard W. ; Marlow, David A. ; Morris JA ; Needham LL ; Patterson DG Jr. ; Piacitelli, Laurie A. ; Sweeney, Marie H.
• Description:
  The results of the analysis of 197 serum samples for 2,3,7,8- tetrachlorodibenzo-p-dioxin (1746016) (TCDD) were reported. These samples were taken from 143 workers and 54 unexposed referents in the New Jersey and Missouri cohorts. Workers in this analysis were employed at either of two facilities located in Newark, New Jersey or Venona, Missouri. Both facilities produced sodium- trichlorophenol (1320792) and 2,4,5-trichlorophenoxyacetic-acid (93765). The mean serum TCDD level for all workers was 251.7 parts per trillion (ppt) and for all referents combined it was 7.8ppt. The mean level of TCDD present in the serum of workers at the date of termination of exposures was 2,600ppt and 870ppt for the New Jersey and Missouri workers, respectively. The levels in the workers were correlated significantly with the duration of exposure to the TCDD contaminated processes. [Description provided by NIOSH]
• Subjects:
  Agriculture Environmental Pollution Hematologic Tests Insecticides Manufacturing And Industrial Facilities Occupational Exposure Occupational Health Safety
• Keywords:
  3 7 8-TCDD Levels Agricultural-chemicals Author Keywords: Cross-sectional Medical Study Blood-analysis Blood-serum Chemical-industry-workers Chlorinated-hydrocarbon-pesticides Dioxin Environmental-contamination NIOSH-Author Occupational-exposure Occupational Exposure Serum 2

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• ISSN:
  0045-6535
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Georgia ; Missouri ; New Jersey ; Ohio ; OSHA Region 2 ; OSHA Region 4 ; OSHA Region 5 ; OSHA Region 7
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  20
• Issue:
  7
• NIOSHTIC Number:
  nn:00196445
• Citation:
  Chemosphere 1990; 20(7-9):993-1000
• CAS Registry Number:
  2,3,7,8-Tetrachlorodibenzo-p-dioxin (CAS RN 1746-01-6) ; Phenol, trichloro-, sodium salt (1:1) (CAS RN 1320-79-2) ; Trichlorophenoxyacetic acid (CAS RN 93-76-5)
• Federal Fiscal Year:
  1990
• Peer Reviewed:
  True
• Source Full Name:
  Chemosphere
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7571497aab0a895ddd4126a55dcd9e5de104a1f6819f9783fabe936f936e72df5a54ec41baae4b9d8b49d2ec26a70548f97cdf1a1605e277526ac70ef280cc65
• Download URL:
  https://stacks.cdc.gov/view/cdc/204377/cdc_204377_DS1.pdf
• File Type:
  [PDF - 347.65 KB ]