Aerosolized ribavirin - exposures and controls

Details

• Personal Author:
  Decker, John A.
• Description:
  In response to a request for a health hazard evaluation, NIOSH investigators conducted an evaluation of health care worker exposure to ribavirin (36791045) in relation to engineering controls, work practices, and method of administration. Personal air monitoring for aerosolized ribavirin (AR) was carried out in conjunction with the following administration methods: ICN Aerosol Delivery Hood (ADH) with ICN evaluation device in operation, ADH enclosed by the Demistifier scavenging tent, croup tent, and direct coupling to a ventilator. Personal samples were collected in the workers' breathing zone. Exposures to personnel were greatest when ribavirin was administered using the croup tent, less with the ADH, and least with the ventilator or ADH in conjunction with a scavenging tent. Full shift breathing zone concentrations among nurses were related to the amount of time spent in the treatment room, which depended on the severity of the patient's illness and number of children treated at a time. Recommendations were offered for lowering the exposure levels. [Description provided by NIOSH]
• Subjects:
  Air Pollution, Indoor Biopharmaceutics Environmental Health Environmental Monitoring Health Personnel Occupational Health Pharmacies Safety
• Keywords:
  Air-quality-monitoring Air-sampling-equipment Health-care-personnel Indoor-air-pollution Indoor-environmental-quality NIOSH-Author Nurses Pharmaceuticals Pharmacists
• ISSN:
  1047-322X
• Document Type:
  Text
• Genre:
  Journal Article
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  152-155
• Volume:
  7
• Issue:
  3
• NIOSHTIC Number:
  nn:00205682
• Citation:
  Appl Occup Environ Hyg 1992 Mar; 7(3):152-155
• CAS Registry Number:
  Ribavirin (CAS RN 36791-04-5)
• Federal Fiscal Year:
  1992
• Peer Reviewed:
  True
• Source Full Name:
  Applied Occupational and Environmental Hygiene
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:485e9ffc43c25ead5c0305d91013bc19dd2f5a6a30ed5dafc3a4fc59e74ceec63c2a79f2baaf116a10c8c629e38c9324b082a87a7c9ecc5606b4930db37fc487
• Download URL:
  https://stacks.cdc.gov/view/cdc/204093/cdc_204093_DS1.pdf
• File Type:
  [PDF - 635.88 KB ]