The International Nuclear Workers Study (INWORKS): a collaborative epidemiological study to improve knowledge about health effects of protracted low-dose exposure

Details

• Personal Author:
  Cardis E ; Daniels, Robert D. ; Gillies M ; Hamra GB ; Haylock R ; Kesminiene A ; Laurier D ; Leuraud K ; Moissonnier M ; O'Hagan J ; Richardson DB ; Schubauer-Berigan, Mary K. ; Thierry-Chef I
• Description:
  INWORKS is a multinational cohort study, gathering 308 297 workers in the nuclear industry in France, the United Kingdom and the United States of America, with detailed individual monitoring data for external exposure to ionising radiation. Over a mean duration of follow-up of 27 y, the number of observed deaths was 66 632, including 17 957 deaths due to solid cancers, 1791 deaths due to haematological cancers and 27 848 deaths due to cardiovascular diseases. Mean individual cumulative external dose over the period 1945-2005 was 25 mSv. Analyses demonstrated a significant association between red bone marrow dose and the risk of leukaemia (excluding chronic lymphocytic leukaemia) and between colon dose and the risk of solid cancers. INWORKS assembled some of the strongest evidence to strengthen the scientific basis for the protection of adults from low dose, low-dose rate, exposures to ionising radiation. [Description provided by NIOSH]
• Subjects:
  Cardiovascular Diseases Cardiovascular System Environmental Exposure Morbidity Mortality Neoplasms Occupational Health Radiation Risk Assessment Risk Factors Safety Workplace

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• Keywords:
  Bone Marrow Cancer Cancer Rates Cardiovascular Disease Exposure Levels Fatalities Ionizing Radiation Monitoring Systems Morbidity Rates Mortality Rates Nuclear Hazards Nuclear Power Plants Radiation Exposure Risk Factors Work Environment Workers

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• ISSN:
  0144-8420
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  North Carolina ; Ohio ; OSHA Region 3 ; OSHA Region 4 ; OSHA Region 5 ; Pennsylvania
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies ; EID - Education and Information Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  21-25
• Volume:
  173
• Issue:
  1
• NIOSHTIC Number:
  nn:20049073
• Citation:
  Radiat Prot Dosim 2017 Apr; 173(1-3):21-25
• Contact Point Address:
  Dominique Laurier, Institut de Radioprotection et de Sûreté Nucléaire (IRSN), 91190 Fontenay-aux-Roses, France
• Email:
  Dominique.laurier@irsn.fr
• Federal Fiscal Year:
  2017
• Performing Organization:
  University of North Carolina, Chapel Hill
• Peer Reviewed:
  True
• Start Date:
  20110901
• Source Full Name:
  Radiation Protection Dosimetry
• End Date:
  20140630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:24f7c3d7fb556f95522dcd1af47c96fea927906d976bcbb9d71aff15c5397e007652c5fcbde849ff20815f45efb3288fa976105cd02e398a9a644dab1cd0969c
• Download URL:
  https://stacks.cdc.gov/view/cdc/203648/cdc_203648_DS1.pdf
• File Type:
  [PDF - 130.10 KB ]