A review of mortality associated with elongate mineral particle (EMP) exposure in occupational epidemiology studies of gold, talc, and taconite mining

Details

• Personal Author:
  Alexander BH ; Mandel JH ; Ramachandran G
• Description:
  Background: Mining of gold, taconite, and talc may involve exposure to elongate mineral particles (EMP). The involved EMPs are typically non-asbestiform, include dimensions that regulatory definitions exclude, and have been less studied. Methods: A review of the literature was undertaken for this exposure and occupational epidemiological studies that occur in gold, talc, and taconite mining. Results: Quantitative EMP exposure information in these industries is incomplete. However, there are consistent findings of pneumoconiosis in each of these types of mining. A recent case-control study suggests a possible association between this exposure and mesothelioma. Lung cancer is inconsistently reported in these industries and is an unlikely outcome of non-asbestiform EMP exposure. There is evidence of cardiovascular mortality excess across all of these types of mining. Conclusions: Non-malignant respiratory disease and cardiovascular mortality have been consistently increased in these industries. Further investigation, including additional insights for the role of non-asbestiform EMP, is warranted. [Description provided by NIOSH]
• Subjects:
  Cardiovascular Diseases Cardiovascular System Dust Environmental Exposure Epidemiology Lung Lung Diseases Minerals Mining Neoplasms Occupational Health Particulate Matter Respiratory System Respiratory Tract Diseases Risk Assessment Risk Factors Safety Talc

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• Keywords:
  Author Keywords: Mining Cancer Cardiovascular Disease Cardiovascular System Cardiovascular System Disease Cardiovascular System Disorders Elongate Mineral Particle Exposure Assessment Exposure Levels Gold Gold Mines Gold Mining Lung Disease Lung Disorders Mesothelioma Mineral Dusts Mining Industry Non-asbestiform Particulates Pneumoconiosis Pulmonary System Pulmonary System Disorders Respiratory System Disorders Risk Factors Taconite Taconite Mining Talc Mining

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• ISSN:
  0271-3586
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Minnesota ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  59
• Issue:
  12
• NIOSHTIC Number:
  nn:20048812
• Citation:
  Am J Ind Med 2016 Dec; 59(12):1047-1060
• Contact Point Address:
  Jeffrey H. Mandel, MD, MPH, Division of Environmental Health Sciences, University of Minnesota School of Public Health, 420 Delaware Street, S.E., Box 807 Mayo, Minneapolis, MN 55455
• Email:
  mand0125@umn.edu
• CAS Registry Number:
  Gold (CAS RN 7440-57-5) ; Taconite (CAS RN 12249-26-2) ; Talc (Mg3H2(SiO3)4) (CAS RN 14807-96-6)
• Federal Fiscal Year:
  2017
• Performing Organization:
  University of Minnesota
• Peer Reviewed:
  True
• Start Date:
  20140501
• Source Full Name:
  American Journal of Industrial Medicine
• End Date:
  20180715
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d735f18968d6610433d3c102e654543f522c6c4361bdb7151cbc1a27c0b30a62e89b813e66839c0618d05e4ce0a002fba50644bbaf91352f044693580a48cf2c
• Download URL:
  https://stacks.cdc.gov/view/cdc/203443/cdc_203443_DS1.pdf
• File Type:
  [PDF - 2.74 MB ]