Effect of asthma and PTSD on persistence and onset of gastroesophageal reflux symptoms among adults exposed to the September 11, 2001, terrorist attacks

Details

• Personal Author:
  Brackbill RM ; Cone, James E. ; Farfel MR ; Jordan HT ; Li J ; Stellman SD
• Description:
  Background: Little is known about the direction of causality among asthma, posttraumatic stress disorder (PTSD), and onset of gastroesophageal reflux symptoms (GERS) after exposure to the 9/11/2001 World Trade Center (WTC) disaster. Methods: Using data from the WTC Health Registry, we investigated the effects of early diagnosed post-9/11 asthma and PTSD on the late onset and persistence of GERS using log-binomial regression, and examined whether PTSD mediated the asthma-GERS association using structural equation modeling. Results: Of 29,406 enrollees, 23% reported GERS at follow-up in 2011-2012. Early post-9/ 11 asthma and PTSD were each independently associated with both the persistence of GERS that was present at baseline and the development of GERS in persons without a prior history. PTSD mediated the association between early post-9/11 asthma and late-onset GERS. Conclusions: Clinicians should assess patients with post-9/11 GERS for comorbid asthma and PTSD, and plan medical care for these conditions in an integrated fashion. [Description provided by NIOSH]
• Subjects:
  Aging Asthma Environmental Exposure Men Occupational Health Respiratory System Respiratory Tract Diseases Safety September 11 Terrorist Attacks Women
• Keywords:
  Age Groups Asthma Author Keywords: Gastroesophageal Reflux Bronchial Asthma Exposure Levels Gastroesophageal Reflux Disease GERD Humans Post-traumatic Stress Disorder PTSD Terrorist Attacks World Trade Center WTC

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• ISSN:
  0271-3586
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  59
• Issue:
  9
• NIOSHTIC Number:
  nn:20048592
• Citation:
  Am J Ind Med 2016 Sep; 59(9):805-814
• Contact Point Address:
  Jiehui Li, MBBS, MSc, New York City Department of Health and Mental Hygiene, 42-09 28th Street, Queens, NY 11101-4132
• Email:
  jli3@health.nyc.gov
• Federal Fiscal Year:
  2016
• Performing Organization:
  New York City Health/Mental Hygiene
• Peer Reviewed:
  True
• Start Date:
  20090430
• Source Full Name:
  American Journal of Industrial Medicine
• End Date:
  20260630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:18926692091d9c4b1a145b27d6de194b549324b51b4b5bd6a48ece9a6d83c6d404e066e3cc57a4b57937376a8f88ab60bf0a919e7f44ef361e16bd45514ff289
• Download URL:
  https://stacks.cdc.gov/view/cdc/203313/cdc_203313_DS1.pdf
• File Type:
  [PDF - 176.86 KB ]