Antisynthetase antibodies in World Trade Center rescue and recovery workers with inflammatory myositis: comment on the article by Webber et al by Selva-O'Callaghan et al - reply Webber et al

Details

• Personal Author:
  Berman J ; Jaber N ; Prezant DJ ; Qayyum B ; Webber MP
• Description:
  We thank Drs. Selva-O'Callaghan, Labirua-Iturburu, and Pinal-Fernandez for their question regarding the prevalence of antisynthetase antibodies (anti-Jo-1, anti-PL-7, or anti-PL- 12) in the 8 patients in whom inflammatory myopathies were diagnosed after they worked at theWorld Trade Center disaster site (Webber MP, Moir W, Zeig-Owens R, Glaser MS, Jaber N, Hall C, et al. Nested case-control study of selected systemic autoimmune diseases in World Trade Center rescue/recovery workers. Arthritis Rheumatol 2015;67:1369-76). We do not have access to the records of these patients, because care for rheumatologic disease occurred outside of the Fire Department of the City of New York health program. For any diagnosis of systemic autoimmune disease, we required a specific written diagnosis from the treating physician (either an internist or a rheumatologist) and supporting documentation that only sometimes included blood test results for antisynthetase antibodies (anti-Jo-1, anti-PL-7, or anti-PL-12) and in other cases included confirmation of biopsy results. Accordingly, we had positive anti-Jo-1 results for 2 patients, negative anti-Jo-1 results for 3 others, and were missing antisynthetase antibody results for the remaining 3 patients. Biopsies were performed in 7 patients. [Description provided by NIOSH]
• Subjects:
  Antibodies Blood Hematologic Tests Occupational Health Safety September 11 Terrorist Attacks
• Keywords:
  Biopsy Blood Tests Disaster Response Disaster Sites Diseases World Trade Center WTC
• ISSN:
  2326-5191
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  67
• Issue:
  10
• NIOSHTIC Number:
  nn:20048374
• Citation:
  Arthritis Rheumatol 2015 Oct; 67(10):2791
• Contact Point Address:
  Mayris P. Webber, DrPH, MPH,Montefiore Medical Center & Albert Einstein College of Medicine, Fire Department of the City of New York, 9 Metrotech Center, Brooklyn, NY 11201
• Federal Fiscal Year:
  2016
• Performing Organization:
  Albert Einstein College of Medicine, New York
• Peer Reviewed:
  False
• Start Date:
  20130701
• Source Full Name:
  Arthritis and Rheumatology
• End Date:
  20150630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:efade0458f49eb92b11edce8d2958707927bc3f384ef623b0a3f5cfb6fab350566b0511ada35d220f950367bc78702ab3dcb76cf7bcdea2377359a8877032f0c
• Download URL:
  https://stacks.cdc.gov/view/cdc/203139/cdc_203139_DS1.pdf
• File Type:
  [PDF - 30.13 KB ]