Sex differences in asthma and gastroesophageal reflux disease incidence among the World Trade Center Health Program general responder cohort

Details

• Personal Author:
  Crane MA ; Dasaro CR ; Icitovic N ; Jiang J ; Kaplan JR ; Lucchini RG ; Luft BJ ; Moline JM ; Pendem L ; Shapiro M ; Teitelbaum SL ; Todd AC ; Udasin IG
• Description:
  Background: Asthma and gastroesophageal reflux disease (GERD) are two common conditions among the responders to the WTC attacks. This study examined whether the cumulative incidence rates of asthma and GERD differed by sex among 24,022 and 23,557 WTC responders, respectively. Methods: Cox proportional hazards regression was used to examine the sex difference in the rate of onset of physician-diagnosed asthma or GERD, from 9/12/2001 through 12/31/2015. Results: The cumulative incidence of asthma reached 23% for women and 17% for men by the end of 2015, and the cumulative incidence of GERD reached 38% for women and 45% for men. Comparing women to men, the hazard ratio was 1.48 (95% confidence interval (CI): 1.27, 1.74) for asthma, and 1.25 (95% CI: 1.13, 1.38) for GERD. Conclusions: WTC general responders have a substantial burden of asthma and GERD, with higher incidence in women. [Description provided by NIOSH]
• Subjects:
  Aging Asthma Cohort Studies Diagnosis Emergency Responders Epidemiology Firefighters Law Enforcement Men Occupational Health Respiratory System Respiratory Tract Diseases Safety September 11 Terrorist Attacks Sex Characteristics Women

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• Keywords:
  9/11 Age Groups Author Keywords: Asthma Bronchial Asthma Clinical Diagnosis Cohort Studies Emergency-responders Fire-fighters Gastroesophageal Reflux Disease Gender Factors GERD Humans Mathematical Models Paramedical-services Police-officers Rescue Workers Respiratory System Disorders Sex Factors Statistical-analysis Surveillance-programs Worker Health World Trade Center WTC

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• ISSN:
  0271-3586
• Document Type:
  Text
• Funding:
  Cooperative Agreement ; Contract
• Genre:
  Journal Article
• Place as Subject:
  New Jersey ; New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  59
• Issue:
  9
• NIOSHTIC Number:
  nn:20048356
• Citation:
  Am J Ind Med 2016 Sep; 59(9):815-822
• Contact Point Address:
  Susan L. Teitelbaum, PhD, Department of Preventive Medicine, Icahn School of Medicine at Mount Sinai, One, Gustave L. Levy Place, Box1057, NY 10029
• Email:
  susan.teitelbaum@mssm.edu
• Federal Fiscal Year:
  2016
• Performing Organization:
  State University of New York Stony Brook
• Peer Reviewed:
  True
• Start Date:
  20040715
• Source Full Name:
  American Journal of Industrial Medicine
• End Date:
  20110630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:3b694f941f849853c5960923c5ccdc6ba319ceb95389ddfee6c5c62608a151766c74089bb6f629d90f9615f35b5f4789a35f3c94043491bb0ac00aa4ee81648d
• Download URL:
  https://stacks.cdc.gov/view/cdc/203124/cdc_203124_DS1.pdf
• File Type:
  [PDF - 499.33 KB ]