Shiftwork and decline in endothelial function among police officers
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2016/11/01
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Description:Background: Our objective was to assess the influence of shiftwork on change in endothelial function. Methods: This longitudinal study was conducted in 188 police officers (78.2% men). Shiftwork status (day, afternoon, night) was assessed objectively using daily Buffalo, NY payroll work history records. Brachial artery flow-mediated dilation (FMD) was assessed using ultrasound. Mean change in FMD% between 2004-2009 and 2010-2015 was compared across shiftwork using analysis of variance/covariance. Results: Overall, mean FMD% decreased from 5.74+2.83 to 3.88+2.11 over an average of 7 years among all officers; P<0.0001. Effect modification by gender was significant. Among men (but not women), those who worked day shifts had a smaller mean (+SE) decrease in FMD% (-0.89+0.35) compared with those who worked the afternoon (-2.69+0.39; P=0.001) or night shifts (-2.31+0.45; P=0.020) after risk factor adjustment. Conclusions: Larger declines in endothelial function were observed among men who worked afternoon or night shifts. Further investigation is warranted. [Description provided by NIOSH]
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ISSN:0271-3586
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Volume:59
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Issue:11
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NIOSHTIC Number:nn:20048096
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Citation:Am J Ind Med 2016 Nov; 59(11):1001-1008
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Contact Point Address:Luenda E.Charles, PhD, MPH, U.S. Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, HELD/BEB, MS L-4050, 1095 Willowdale Rd., Morgantown, WV 26505-2888
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Email:lcharles@cdc.gov
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Federal Fiscal Year:2017
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Performing Organization:State University of New York at Buffalo
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Peer Reviewed:True
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Start Date:20100901
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Source Full Name:American Journal of Industrial Medicine
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End Date:20150831
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Main Document Checksum:urn:sha-512:a227517aea136b2a666d4fe6be9b2390e37036fdcf4ef3de1baeac2ca6dbd9a12fcb42d4a5d1f4be31a67504926488fcae8b45357dea7d4b83c8431a72c2fa36
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