A dosimetry study of deuterium-deuterium neutron generator-based in vivo neutron activation analysis

Details

• Personal Author:
  Blake S ; Liu Y ; Mostafaei F ; Nie LH ; Sowers D
• Description:
  A neutron irradiation cavity for in vivo neutron activation analysis (IVNAA) to detect manganese, aluminum, and other potentially toxic elements in human hand bone has been designed and its dosimetric specifications measured. The neutron source is a customized deuterium-deuterium neutron generator that produces neutrons at 2.45 MeV by the fusion reaction 2H(d, n)3He at a calculated flux of 7 × 10(8) +/- 30% s(-1). A moderator/reflector/shielding [5 cm high density polyethylene (HDPE), 5.3 cm graphite and 5.7 cm borated (HDPE)] assembly has been designed and built to maximize the thermal neutron flux inside the hand irradiation cavity and to reduce the extremity dose and effective dose to the human subject. Lead sheets are used to attenuate bremsstrahlung x rays and activation gammas. A Monte Carlo simulation (MCNP6) was used to model the system and calculate extremity dose. The extremity dose was measured with neutron and photon sensitive film badges and Fuji electronic pocket dosimeters (EPD). The neutron ambient dose outside the shielding was measured by Fuji NSN3, and the photon dose was measured by a Bicron MicroREM scintillator. Neutron extremity dose was calculated to be 32.3 mSv using MCNP6 simulations given a 10-min IVNAA measurement of manganese. Measurements by EPD and film badge indicate hand dose to be 31.7 +/- 0.8 mSv for neutrons and 4.2 +/- 0.2 mSv for photons for 10 min; whole body effective dose was calculated conservatively to be 0.052 mSv. Experimental values closely match values obtained from MCNP6 simulations. These are acceptable doses to apply the technology for a manganese toxicity study in a human population. [Description provided by NIOSH]
• Subjects:
  Occupational Health Radiation Dosimeters Safety
• Keywords:
  Author Keywords: Mixed Field Dosimetry Dosimetry Neutron Activation Neutron Detection Neutron Dosimetry Neutron Radiation Radiation Exposure Radiation Measurement Radiation Monitoring Radiation Monitors
• ISSN:
  0017-9078
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Indiana ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  109
• Issue:
  6
• NIOSHTIC Number:
  nn:20047689
• Citation:
  Health Phys 2015 Dec; 109(6):566-572
• Contact Point Address:
  Daniel Sowers, School of Health Sciences, Purdue University, 550 Stadium Mall Drive, West Lafayette, IN 47907
• Email:
  dsowers@purdue.edu
• Federal Fiscal Year:
  2016
• Performing Organization:
  Purdue University, West Lafayette, Indiana
• Peer Reviewed:
  True
• Start Date:
  20120701
• Source Full Name:
  Health Physics
• End Date:
  20150630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:4350f60c3b74ead4cb8ce2ea65f322286f5d86fbca12512ef98f67b248e0d575af58ae88620f2740c5d28db7d88d44b350645d8e3179443f8da366a614b2a240
• Download URL:
  https://stacks.cdc.gov/view/cdc/202692/cdc_202692_DS1.pdf
• File Type:
  [PDF - 398.17 KB ]