Long-lasting permethrin-impregnated clothing protects against mosquito bites in outdoor workers

Details

• Personal Author:
  Apperson C ; Colpitts TM ; Funkhauser S ; Grippin C ; Jameson SB ; Londono-Renteria B ; Meshnick SR ; Mores CN ; Patel JC ; Ponnusamy L ; Vaughn M ; Wesson DM
• Description:
  Outdoor exposure to mosquitoes is a risk factor for many diseases, including malaria and dengue. We have previously shown that long-lasting permethrin-impregnated clothing protects against tick and chigger bites in a double-blind randomized controlled trial in North Carolina outdoor workers. Here, we evaluated whether this clothing is protective against mosquito bites by measuring changes in antibody titers to mosquito salivary gland extracts. On average, there was a 10-fold increase in titer during the spring and summer when mosquito exposure was likely to be the highest. During the first year of the study, the increase in titer in subjects wearing treated uniforms was 2- to 2.5-fold lower than that of control subjects. This finding suggests that long-lasting permethrin-impregnated clothing provided protection against mosquito bites. [Description provided by NIOSH]
• Subjects:
  Antibodies Disease Vectors Environmental Exposure Environmental Pollution Insecta Laboratories Occupational Exposure Occupational Health Personal Protective Equipment Protective Clothing Safety

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• Keywords:
  Antibody-response Clothing Disease-vectors Employee-exposure Environmental-exposure Environmental-hazards Humans Insect-repellents Insects Laboratory-testing Outdoors Personal-protective-equipment Pests Protective-clothing Pyrethroids Seasonal-activity

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• ISSN:
  0002-9637
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Louisiana ; North Carolina ; OSHA Region 4 ; OSHA Region 6 ; South Carolina
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  93
• Issue:
  4
• NIOSHTIC Number:
  nn:20047492
• Citation:
  Am J Trop Med Hyg 2015 Oct; 93(4):869-874
• Contact Point Address:
  Berlin Londono-Renteria, Department of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, 6439 Garners Ferry Rd, Bldg 2, Columbia, SC 29209
• Email:
  berlinlondo@yahoo.com
• CAS Registry Number:
  Permethrin (CAS RN 52645-53-1)
• Federal Fiscal Year:
  2016
• Performing Organization:
  University of North Carolina, Chapel Hill
• Peer Reviewed:
  True
• Start Date:
  20100901
• Source Full Name:
  The American Journal of Tropical Medicine and Hygiene
• End Date:
  20150831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:3f08b93b5a64e537ba1d77c1548b95f234c0d3115eea32eeca2506aabb37bdb095182c2ee233bc45477b925dcf57813da3910c2c51e38c9d49df9309d8eface0
• Download URL:
  https://stacks.cdc.gov/view/cdc/202545/cdc_202545_DS1.pdf
• File Type:
  [PDF - 627.27 KB ]