Association between cardiovascular risk factors and carpal tunnel syndrome in pooled occupational cohorts

Details

• Personal Author:
  Bao S ; Drury DL ; Foster J ; Garg, Arun ; Hegmann KT ; Kapellusch J ; Kendall R ; Merryweather AS ; Silverstein B ; Thiese MS ; Wertsch J ; Wood EM
• Description:
  Objective: The aim of the study was to ascertain if cardiovascular (CVD) risk factors are carpal tunnel syndrome (CTS) risk factors. Methods: Analysis of pooled baseline data from two large prospective cohort studies (n=1824) assessed the relationships between a modified Framingham Heart Study CVD risk score both CTS and abnormal nerve conduction study prevalence. Quantified job exposures, personal and psychosocial confounders were statistically controlled. Odds ratio and 95% confidence intervals were calculated for individual risk scores. Results: There was a strong relationship between CVD risk score and both CTS and abnormal nerve conduction study after adjustment for confounders, with odds ratios as high as 4.16 and 7.35, respectively. Dose responses were also observed. Conclusions: In this workplace population, there is a strong association between CVD risk scores and both CTS and abnormal nerve conduction study that persisted after controlling for confounders. These data suggest a potentially modifiable disease mechanism. [Description provided by NIOSH]
• Subjects:
  Cardiovascular Diseases Cardiovascular System Demography Musculoskeletal Diseases Musculoskeletal System Occupational Exposure Occupational Health Risk Assessment Risk Factors Safety
• Keywords:
  Cardiovascular-system-disease Cardiovascular-system-disorders Carpal-tunnel-syndrome Demographic-characteristics Dose-response Employee-exposure Heart Humans Musculoskeletal-system-disorders Nerve-function Risk-factors Statistical-analysis Statistical-quality-control Workers

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• ISSN:
  1076-2752
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; Minnesota ; OSHA Region 10 ; OSHA Region 5 ; OSHA Region 8 ; OSHA Region 9 ; Utah ; Washington ; Wisconsin
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  87-93
• Volume:
  58
• Issue:
  1
• NIOSHTIC Number:
  nn:20047188
• Citation:
  J Occup Environ Med 2016 Jan; 58(1):87-93
• Contact Point Address:
  Kurt T. Hegmann, MD, MPH, Rocky Mountain Center for Occupational and Environmental Health, Department of Family and Preventive Medicine, School of Medicine, University of Utah, 391 Chipeta Way, Suite C, Salt Lake City, UT 84108
• Email:
  kurt.hegmann@hsc.utah.edu
• Federal Fiscal Year:
  2016
• Performing Organization:
  University of California-San Francisco
• Peer Reviewed:
  True
• Start Date:
  20100901
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• End Date:
  20140831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:6e888fd969744466d2862139cff9d24bef49499bce5b3b6010e56604c7d2efbefa91d3d9becdea07c61ffdabf486c6bc096a8c3dfa28db44d10fb2301df7f7b3
• Download URL:
  https://stacks.cdc.gov/view/cdc/202350/cdc_202350_DS1.pdf
• File Type:
  [PDF - 188.83 KB ]