Hearing in older adults with exfoliation syndrome/exfoliation glaucoma or primary open-angle glaucoma

Details

• Personal Author:
  Cotch MF ; Eiriksdottir G ; Gudnason V ; Harris TB ; Hoffman HJ ; Jonasson F ; Launer LJ ; Li C-M ; Petersen H ; Sverrisdottir JE ; Themann, Christa L. ; Tryggvason G
• Description:
  PURPOSE: To determine whether adults, aged 66-96 years, with exfoliation syndrome (XFS)/exfoliation glaucoma (XFG), or primary open-angle glaucoma (POAG) have poorer hearing than controls of similar age. METHODS: Case (XFS/XFG and POAG) and control status was diagnosed in the Reykjavik Glaucoma Studies (RGS) using slit-lamp examination, visual field testing and optic disc photographs; the RGS data were merged with the Age, Gene/Environment Susceptibility-Reykjavik Study that collected hearing data using air-conduction, pure-tone thresholds obtained at 0.5, 1, 2, 3, 4, 6 and 8 kHz categorized by better ear and worse ear, based on pure-tone averages (PTAs) calculated separately for low and middle frequencies (PTA512 - mean of thresholds at 0.5, 1 and 2 kHz) and high frequencies (PTA3468 - mean of thresholds at 3, 4, 6 and 8 kHz). Multivariable linear regression was used to test for differences in PTAs between cases and controls. RESULTS: The mean age for 158 XFS/XFG cases (30.4% male) was 77.4 years, 95 POAG cases (35.8% male) was 77.9 years, and 123 controls (46.3% male) was 76.8 years. Using multivariable linear regression analysis, there were no consistent, statistically significant differences in PTAs between the two case groups and controls in either the low- or high-frequency range, even when stratified by age group. CONCLUSION: Among the older individuals examined in this study hearing loss is highly prevalent and strongly associated with male gender and increasing age. As we did not find consistent statistically significant difference in hearing between cases and controls the diagnosis of XFS/XFG or POAG does not as such routinely call for audiological evaluation. [Description provided by NIOSH]
• Subjects:
  Aging Ear Environmental Exposure Genetics Hearing Hearing Loss Men Occupational Health Safety Sense Organs Women

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• Keywords:
  Age-groups Author Keywords: Adjustment For Age And Sex Ear-disorders Ear-examinations Ears Environmental-exposure Exfoliation Glaucoma Genes Hearing-acuity Hearing-level Hearing-loss Humans Primary Open-angle Glaucoma Statistical-analysis

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• ISSN:
  1755-375X
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Maryland ; Ohio ; OSHA Region 3 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DART - Division of Applied Research and Technology
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  140-146
• Volume:
  94
• Issue:
  2
• NIOSHTIC Number:
  nn:20047096
• Citation:
  Acta Ophthalmol 2016 Mar; 94(2):140-146
• Contact Point Address:
  Fridbert Jonasson, MD, Department of Ophthalmology, Landspitali University Hospital, Reykjavik, Iceland
• Email:
  fridbert@landspitali.is
• Federal Fiscal Year:
  2016
• Peer Reviewed:
  True
• Source Full Name:
  Acta Ophthalmologica
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:9d050fa68ba092bfccb5741125a21c630227c5335283573eb28d3f553211c2836df1b9afda917ca21e912c6abb3f321c990e4ae33ae25e281be68c9a88734823
• Download URL:
  https://stacks.cdc.gov/view/cdc/202293/cdc_202293_DS1.pdf
• File Type:
  [PDF - 151.96 KB ]