Antiviral drugs
Public Domain
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2015/11/13
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Details
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Personal Author:
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Description:Topical cidofovir treatment in herpes simples virus infections resulted in irreversible acute kidney injury. A 58-year-old man underwent a matched unrelated donor (MUD) stem cell transplant for secondary myelodysplastic syndrome. His conditioning regimen consisted of busulfan, fludarabine, and antithymocyte globulin. The patient received oral valganciclovir during the peritransplantation phase at a dose of 900 mg twice daily for CMV prophylaxis, and prophylactic valacyclovir was initiated on day 1. The patient was readmitted within 2 weeks of his initial hospital discharge with neutropenic fever, worsening mucositis, and acute cutaneous graft-versushost disease (GVHD). The patient was treated with intravenous (IV) acyclovir at 5 mg/kg followed by antiviral therapy containing 5% cidofovir administered as oral gel. [Description provided by NIOSH]
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ISBN:9780444635259
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ISSN:0378-6080
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Pages in Document:329-348
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Volume:37
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NIOSHTIC Number:nn:20047032
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Citation:Side effects of drugs annual: a worldwide yearly survey of new data in adverse drug reactions, first edition. Ray SD, Gray JP, Kiersma ME, Dukes MNG, eds. Waltham, MA: Elsevier, 2015 Nov; 37:329-348
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Contact Point Address:Sreekumar Othumpangat, Allergy and Clinical Immunology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 1095 Willowdale Road, Morgantown, WV 26505
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Email:seo8@cdc.gov
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Federal Fiscal Year:2016
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Peer Reviewed:True
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Source Full Name:Side effects of drugs annual: a worldwide yearly survey of new data in adverse drug reactions, first edition
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Main Document Checksum:urn:sha-512:cdb2d1fbeef1577f33cda4253a4ecab15012edc0a46d56995706e6149939ca313e1b86fb0af29d3759167bcaf589a9e79977aaa6b7f3d439aea52f3fe859c23a
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