Respiratory morbidity in a coffee processing workplace with sentinel obliterative bronchiolitis cases

Details

• Personal Author:
  Bailey, Rachel L. ; Bledsoe TA ; Cox-Ganser, Jean M. ; Duling, Matthew G. ; Green, Brett J. ; Kreiss, Kathleen ; LeBouf, Ryan F. ; Martin SB Jr.
• Description:
  Rationale: Obliterative bronchiolitis in former coffee workers prompted a cross-sectional study of current workers. Diacetyl and 2,3-pentanedione levels were highest in areas for flavoring and grinding/packaging unflavored coffee. Methods: We interviewed 75 (88%) workers, measured lung function, and created exposure groups based on work history. We calculated standardized morbidity ratios (SMRs) for symptoms and spirometric abnormalities. We examined health outcomes by exposure groups. Results: SMRs were elevated 1.6-fold for dyspnea and 2.7-fold for obstruction. The exposure group working in both coffee flavoring and grinding/packaging of unflavored coffee areas had significantly lower mean ratio of forced expiratory volume in 1s to forced vital capacity and percent predicted mid-expiratory flow than workers without such exposure. Conclusion: Current workers have occupational lung morbidity associated with high diacetyl and 2,3-pentanedione exposures, which were not limited to flavoring areas. [Description provided by NIOSH]
• Subjects:
  Food-Processing Industry Food Additives Food Handling Food Industry Lung Lung Diseases Men Morbidity Occupational Health Respiratory System Respiratory Tract Diseases Risk Assessment Risk Factors Safety Women

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• Keywords:
  2,3-pentanedione Asthma Author Keywords: Obliterative Bronchiolitis Coffee Diacetyl Exposure-levels Flavorings Food-additives Food-processing Food-processing-workers Humans Lung-function Morbidity-rates Pulmonary-disorders Pulmonary-system Pulmonary-system-disorders Respiration Respiratory-system-disorders Risk-factors

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• ISSN:
  0271-3586
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  RHD - Respiratory Health Division ; HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  58
• Issue:
  12
• NIOSHTIC Number:
  nn:20046949
• Citation:
  Am J Ind Med 2015 Dec; 58(12):1235-1245
• Contact Point Address:
  Rachel L. Bailey, DO, MPH, Field Studies Branch, Respiratory Health Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, MS H2800, Morgantown,WV 26505
• Email:
  feu2@cdc.gov
• CAS Registry Number:
  Butanedione (CAS RN 431-03-8)
• Federal Fiscal Year:
  2016
• Peer Reviewed:
  True
• Source Full Name:
  American Journal of Industrial Medicine
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:e06a971bffc7a555f442359dd19a8ce2cc655ee0cfa4c275adaf0083544f5ec4de143ffe08965ad7ff3f2142fa2de3c4c2973197a9a586847ec6c5e3641370fa
• Download URL:
  https://stacks.cdc.gov/view/cdc/202203/cdc_202203_DS1.pdf
• File Type:
  [PDF - 369.50 KB ]