Characterization of silver nanoparticles in selected consumer products and its relevance for predicting children's potential exposures

Details

• Personal Author:
  LeBouf, Ryan F. ; Marr LC ; Mwilu S ; Rogers K ; Schwegler-Berry D ; Stefaniak, Aleksandr B. ; Thomas TA ; Tulve NS ; Vance ME ; Willis R
• Description:
  Due to their antifungal, antibacterial, antiviral, and antimicrobial properties, silver nanoparticles (AgNPsare used in consumer products intended for use by children or in the home. Children may be especially affected by the normal use of consumer products because of their physiological functions, developmental stage, and activities and behaviors. Despite much research to date, children's potential exposures to AgNPs are not well characterized. Our objectives were to characterize selected consumer products containing AgNPs and to use the data to estimate a child's potential non-dietary ingestion exposure. We identified and cataloged 165 consumer products claiming to contain AgNPs that may be used by or near children or found in the home. Nineteen products (textile, liquid, plastic) were selected for further analysis. We developed a tiered analytical approach to determine silver content, form (particulate or ionic), size, morphology, agglomeration state, and composition. Silver was detected in all products except one sippy cup body. Among products in a given category, silver mass contributions were highly variable and not always uniformly distributed within products, highlighting the need to sample multiple areas of a product. Electron microscopy confirmed the presence of AgNPs. Using this data, a child's potential non-dietary ingestion exposure to AgNPs when drinking milk formula from a sippy cup is 1.53 ug Ag/kg. Additional research is needed to understand the number and types of consumer products containing silver and the concentrations of silver in these products in order to more accurately predict children's potential aggregate and cumulative exposures to AgNPs. [Description provided by NIOSH]
• Subjects:
  Diet Occupational Health Safety Silver
• Keywords:
  Antibacterial Agents Antifungals Author Keywords: Children Children Consumer Products Exposure Inventory Nanoparticles Nanosilver Physiology Silver Compounds

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• ISSN:
  1438-4639
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Maryland ; Nevada ; North Carolina ; OSHA Region 3 ; OSHA Region 4 ; OSHA Region 9 ; Virginia ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies ; HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  345-357
• Volume:
  218
• Issue:
  3
• NIOSHTIC Number:
  nn:20046010
• Citation:
  Int J Hyg Environ Health 2015 May; 218(3):345-357
• Contact Point Address:
  Nicolle S. Tulvea, U.S. Environmental Protection Agency, Office of Research and Development, National Exposure Research Laboratory, Research Triangle Park, NC 27711
• Email:
  tulve.nicolle@epa.gov
• CAS Registry Number:
  Silver (CAS RN 7440-22-4)
• Federal Fiscal Year:
  2015
• NORA Priority Area:
  Mining ; Oil and Gas Extraction ; Manufacturing
• Peer Reviewed:
  True
• Source Full Name:
  International Journal of Hygiene and Environmental Health
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:ce7482a89301e27b4cb38206a0047d54f8bc8e34f0caced254beab5da9295604f7c89f9f034146355c36ae61004b934a60c24eef7ef41a3c1eef66be31a04962
• Download URL:
  https://stacks.cdc.gov/view/cdc/201203/cdc_201203_DS1.pdf
• File Type:
  [PDF - 3.08 MB ]