Pulmonary toxicity of graphene nanomaterials: an emerging concern in manufacturing and applications

Details

• Personal Author:
  Erdely A ; Roberts, Jennifer R.
• Description:
  Graphene, a one-atom-thick monolayer of carbon, is an engineered nanomaterial (ENM) with physical and chemical properties that may offer application advantages over other carbonaceous ENMs, such as carbon nanotubes (CNT). As use of graphene nanomaterials (GNMs) in a variety of industries and manufacturing increases, the potential for respiratory exposure, particularly in the workplace, also rises. Unlike CNT, toxicity of GNMs has not been well defined. In addition, GNMs can vary in dimension, surface chemistry, number of layers, and other physico-chemical parameters, which in turn may affect toxicological potency of the material. The goal of this workshop is to present the most recent toxicological research findings in the field of GNMs and gain an understanding of the hazard and risk for exposure. The workshop will cover the physico-chemical characteristics and applications of a variety of GNMs, potential exposure in occupational settings, toxicity related to size and composition following various methods of pulmonary exposure in animal models, and comparative toxicity to well-defined carbonaceous ENMs. The outcome for the session is to establish whether GNM exposure poses a potential health hazard by providing an understanding of GNMs and conveying the most recent material science expertise and toxicological research related to respiratory exposure to various forms of GNMs. [Description provided by NIOSH]
• Subjects:
  Chemistry Environmental Monitoring Hazardous Substances Lung Occupational Health Respiratory System Respiratory Tract Diseases Risk Assessment Risk Factors Safety Toxicology

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• Keywords:
  Carbon-compounds Chemical-composition Chemical-properties Exposure-assessment Health-hazards Nanotechnology Physical-properties Pulmonary-function Pulmonary-system-disorders Respiratory-system-disorders Risk-factors Surface-properties Toxic-effects Toxic-materials

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• ISSN:
  1096-6080
• Document Type:
  Text
• Genre:
  Abstract or Summary
• Place as Subject:
  California ; OSHA Region 3 ; OSHA Region 9 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  144
• Issue:
  1
• NIOSHTIC Number:
  nn:20045904
• Citation:
  Toxicologist 2015 Mar; 144(1):172
• CAS Registry Number:
  Graphene (CAS RN 1034343-98-0)
• Federal Fiscal Year:
  2015
• NORA Priority Area:
  Manufacturing
• Peer Reviewed:
  False
• Source Full Name:
  The Toxicologist. Society of Toxicology 54th Annual Meeting and ToxExpo, March 22-26, 2015, San Diego, California
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:0b95fb8e174be261ab3146bf0059317be3054b2b47f02fea70fc92684aacee218ee7871a96c0ad5ed3e8c5b3c1fbc8822fd39e15ad20395839007df19dc71092
• Download URL:
  https://stacks.cdc.gov/view/cdc/201149/cdc_201149_DS1.pdf
• File Type:
  [PDF - 219.46 KB ]