Accuracy, sensitivity, and specificity of a wrist actigraphy algorithm for sleep/wake and WASO as compared to polysomnography

Details

• Personal Author:
  Berkman L ; Buston OM ; Dulin H ; Ellenbogen JM ; Li-Y ; Marino M ; Rueschman M ; Solet JM ; Winkelman J
• Description:
  Introduction: Published validation studies for existing wrist actigraphy algorithms currently in use are limited. We sought to determine the overall accuracy (epoch-level sensitivity and specificity, and night-level wake after sleep onset [WASO]) of a commonly-used algorithm in a variety of subjects. Methods: Actigraphy (AW-64 and Spectrum uni-dimensional wrist accelerometers. Philips/Respironics: medium sensitivity, Cole-Kripke algorithm) and PSG were collected simultaneously during inpatient sleep laboratory visits of young and older adults, healthy sleep restricted subjects, chronic primary insomniac (PI) patients, and night workers during daytime sleep (n= 77, age 35.0+/- 12.S. 30 F, mean nights= 3.2+/-3.0). All studies involved 8.5 hr Time in Bed except sleep restriction. Epochs (30-second: n=232.849) were characterized for Sensitivity (actigraphy=sleep when PSG=sleep). Specificity (actigraphy=wake when PSG=wake), and Accuracy (total proportion correct): WASO was assessed by night. A generalized estimating equation (GEE) model included age, gender, insomnia diagnosis, and daytime/nighttime sleep timing factors, providing an unbiased estimation of population-averaged regression coefficients. Results: Overall Sensitivity (0.965), Specificity (0.329), and Accuracy (0.863) were only slightly modified by gender and day/night sleep timing (magnitude of change <0.04). Sensitivity, specificity, and accuracy in participants without insomnia, controlling for age, sleep timing and gender (0.967. 0.331. 0.869, respectively), were slightly different than PI patients (0.946. 0.347. 0.833). Age had no meaningful impact on the sensitivity of actigraphy, but demonstrated a minimal effect on the specificity and accuracy as age increased. Mean WASO per night was 49. 1 minutes by PSG compared to 36.8 minutes by actigraphy (Spearman rank correlation, rs=.61 , p
• Subjects:
  Aging Circadian Rhythm Demography Men Mental Health Occupational Health Safety Sleep Sleep Initiation And Maintenance Disorders Stress, Psychological Women

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• Keywords:
  Age-groups Circadian-rhythms Demographic-characteristics Humans Physical-capacity Physical-stress Physiology Psychological-stress Sleep-deprivation Sleep-disorders Sociological-factors Statistical-analysis Stress Workers

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• ISSN:
  0161-8105
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Abstract or Summary
• Place as Subject:
  Massachusetts ; Oregon ; OSHA Region 1 ; OSHA Region 10
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  35
• NIOSHTIC Number:
  nn:20045618
• Citation:
  Sleep 2012 Jun; 35(Abstract Suppl):A440-A441
• Federal Fiscal Year:
  2012
• Performing Organization:
  Portland State University
• Peer Reviewed:
  False
• Start Date:
  20050901
• Source Full Name:
  Sleep
• Supplement:
  Abstract Supplement
• End Date:
  20081130
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:63447c37076b5701ae5a4c7b1171aa4a7ba79353cd6fbd21021b40865e44f9c499d4d340ff28d6f56b57646ac55c9cd886ee775652d004e363deb3cff9105faf
• Download URL:
  https://stacks.cdc.gov/view/cdc/200971/cdc_200971_DS1.pdf
• File Type:
  [PDF - 1.37 MB ]