Investing in prospective cohorts for etiologic study of occupational exposures
Public Domain
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2015/02/01
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Details
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Personal Author:Alavanja MC ; Blair, Austin ; Freeman LE ; Hines CJ ; Hoppin JA ; Kamel F ; Lubin JH ; Lynch CF ; Sandler DP ; Silverman DT ; Thomas KW ; Whelan, Elizabeth A. ; Zahm SH
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Description:Prospective cohorts have played a major role in understanding the contribution of diet, physical activity, medical conditions, and genes to the development of many diseases, but have not been widely used for occupational exposures. Studies in agriculture are an exception. We draw upon our experience using this design to study agricultural workers to identify conditions that might foster use of prospective cohorts to study other occupational settings. Prospective cohort studies are perceived by many as the strongest epidemiologic design. It allows updating of information on exposure and other factors, collection of biologic samples before disease diagnosis for biomarker studies, assessment of effect modification by genes, lifestyle, and other occupational exposures, and evaluation of a wide range of health outcomes. Increased use of prospective cohorts would be beneficial in identifying hazardous exposures in the workplace. Occupational epidemiologists should seek opportunities to initiate prospective cohorts to investigate high priority, occupational exposures. [Description provided by NIOSH]
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ISSN:0271-3586
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Place as Subject:Iowa ; Maryland ; North Carolina ; Ohio ; OSHA Region 3 ; OSHA Region 4 ; OSHA Region 5 ; OSHA Region 7
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Pages in Document:113-122
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Volume:58
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Issue:2
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NIOSHTIC Number:nn:20045564
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Citation:Am J Ind Med 2015 Feb; 58(2):113-122
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Contact Point Address:Dr. Aaron Blair, National Cancer Institute, 9609 Medical Center Drive, Rockville, MD 20892
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Email:blaira@mail.nih.gov
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Federal Fiscal Year:2015
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Peer Reviewed:True
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Source Full Name:American Journal of Industrial Medicine
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Main Document Checksum:urn:sha-512:c4b5ed52cde55092234d355ef9230675c757725904aa400e21887069dae75d7dfd57e0b403e95bb32477c77129be4e73e414e1ce24bffdc90d963b463203480e
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